Evidence map›Paper›PMID 33796096›Full record

ArticleFrontiers in immunology2021

2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.

Wen-I Liao, Shu-Yu Wu, Shih-Hung Tsai, Hsin-Ping Pao, Kun-Lun Huang, Shi-Jye Chu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  5. Animals : an open access journal from MDPI · 2025
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  7. Review
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  9. Article
  10. Protective Effects of 2-Methoxyestradiol on Acute Isoproterenol-Induced Cardiac Injury in Rats.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  11. Article
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  13. Review
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  18. Alda-1 ameliorates air embolism-induced acute lung injury.International journal of immunopathology and pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wen-I LiaoThe Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Shu-Yu WuInstitute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei, Taiwan.
Shih-Hung TsaiDepartment of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Hsin-Ping PaoThe Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Kun-Lun HuangThe Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Shi-Jye ChuDepartment of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
National Defense Medical Center · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung Diseases2-MethoxyestradiolAnimalsAnnexin A1LungMaleRatsRats, Sprague-DawleyReperfusion InjuryUp-Regulation2-MethoxyestradiolAnnexin A12-methoxyestradiolacute lung injuryannexin A1epitheliumischemia and reperfusion

Identifiers

PMID33796096
PMCPMC8007881
OpenAlexW3136750376

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.