Evidence map›Paper›PMID 33796839›Full record

ArticleiScience2021

Dopamine receptor DOP-1 engages a sleep pathway to modulate swimming in

Ye Xu, Lin Zhang, Yan Liu, Irini Topalidou, Cera Hassinan, Michael Ailion, Zhenqiang Zhao, Tan Wang, Zhibin Chen, Jihong Bai

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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  5. Using aPharmaceuticals (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ye XuDepartment of Clinical Medicine, Nanjing Medical University, Nanjing 211166, P. R. China.
Lin ZhangBasic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., Seattle, WA 98109, USA.
Yan LiuBasic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., Seattle, WA 98109, USA.
Irini TopalidouDepartment of Biochemistry, University of Washington, WA 98195.
Cera HassinanBasic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., Seattle, WA 98109, USA.
Michael AilionDepartment of Biochemistry, University of Washington, WA 98195.
Zhenqiang ZhaoDepartment of Neurology, First Affiliated Hospital of Hainan Medical University, Hainan Medical University, Hainan 570102, P. R. China.
Tan WangDepartment of Neurology, First Affiliated Hospital of Hainan Medical University, Hainan Medical University, Hainan 570102, P. R. China.
Zhibin ChenDepartment of Clinical Medicine, Nanjing Medical University, Nanjing 211166, P. R. China.
Jihong BaiBasic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., Seattle, WA 98109, USA.
University of Washington · USFred Hutch Cancer Center · USHainan Medical University · CN

Funding

Signaling Pathways that Modulate Neuronal ActivityR01NS109476 · NINDS · UNIVERSITY OF WASHINGTON · PI Michael Ailion, Jihong Bai · 2020 to 2026
$2.5M
NINDS NIH HHS R01 NS109476
6 · The paper itself

Abstract

Animals require robust yet flexible programs to support locomotion. Here we report a pathway that connects the D1-like dopamine receptor DOP-1 with a sleep mechanism to modulate swimming in

Indexed as

Behavioral NeuroscienceBiological SciencesNeuroscience

Identifiers

PMID33796839
PMCPMC7995527
OpenAlexW3134183560

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.