Evidence map›Paper›PMID 33799503›Full record

ReviewInternational journal of molecular sciences2021

Growth Hormone and the Auditory Pathway: Neuromodulation and Neuroregeneration.

Joaquín Guerra Gómez, Jesús Devesa

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joaquín Guerra GómezOtolaryngology, Medical Center Foltra, 15886 Teo, Spain.ORCID 0000-0003-2340-0595
Jesús DevesaScientific Direction, Medical Center Foltra, 15886 Teo, Spain.ORCID 0000-0002-4153-2543

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth hormone (GH) plays an important role in auditory development during the embryonic stage. Exogenous agents such as sound, noise, drugs or trauma, can induce the release of this hormone to perform a protective function and stimulate other mediators that protect the auditory pathway. In addition, GH deficiency conditions hearing loss or central auditory processing disorders. There are promising animal studies that reflect a possible regenerative role when exogenous GH is used in hearing impairments, demonstrated in in vivo and in vitro studies, and also, even a few studies show beneficial effects in humans presented and substantiated in the main text, although they should not exaggerate the main conclusions.

Indexed as

AnimalsAuditory CortexAuditory PathwaysCochleaCochlear NerveGene Expression RegulationGrowth HormoneHearing Loss, FunctionalHearing Loss, SensorineuralHippocampusHumansInsulin-Like Growth Factor INerve RegenerationNoiseGrowth HormoneInsulin-Like Growth Factor Icentral auditory processingGH deficiencygrowth hormonehearing impairmenthereditary hearing lossIGF-I

Identifiers

PMID33799503
PMCPMC7998811
OpenAlexW3133811150

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.