Evidence map›Paper›PMID 33800668›Full record

ReviewNutrients2021

Mechanisms of Food-Induced Symptom Induction and Dietary Management in Functional Dyspepsia.

Kerith Duncanson, Grace Burns, Jennifer Pryor, Simon Keely, Nicholas J Talley

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 5 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Prevalence ofIranian journal of microbiology · 2025
    Article
  13. Article
  14. Innovative concepts in diet therapies in disorders of gut-brain interaction.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Review
  15. Nutraceuticals and biotics in pediatric gastrointestinal disorders.European journal of clinical nutrition · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kerith DuncansonCollege of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0001-5525-6589
Grace BurnsCollege of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW 2308, Australia.
Jennifer PryorCollege of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW 2308, Australia.
Simon KeelyCollege of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0002-1248-9590
Nicholas J TalleyCollege of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0003-2537-3092
Hunter Medical Research Institute · AUJohn Hunter Hospital · AU

Funding

National Health and Medical Research Council 1170893
6 · The paper itself

Abstract

Functional dyspepsia (FD) is a common disorder of gut-brain interaction, characterised by upper gastrointestinal symptom profiles that differentiate FD from the irritable bowel syndrome (IBS), although the two conditions often co-exist. Despite food and eating being implicated in FD symptom induction, evidence-based guidance for dietetic management of FD is limited. The aim of this narrative review is to collate the possible mechanisms for eating-induced and food-related symptoms of FD for stratification of dietetic management. Specific carbohydrates, proteins and fats, or foods high in these macronutrients have all been reported as influencing FD symptom induction, with removal of 'trigger' foods or nutrients shown to alleviate symptoms. Food additives and natural food chemicals have also been implicated, but there is a lack of convincing evidence. Emerging evidence suggests the gastrointestinal microbiota is the primary interface between food and symptom induction in FD, and is therefore a research direction that warrants substantial attention. Objective markers of FD, along with more sensitive and specific dietary assessment tools will contribute to progressing towards evidence-based dietetic management of FD.

Indexed as

DietDiet TherapyDyspepsiaFoodHumansdietary managementfunctional dyspepsiagastrointestinal symptoms

Identifiers

PMID33800668
PMCPMC8066021
OpenAlexW3149479869

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.