ReviewBiomolecules2021
The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue.
Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
154 citing papers in PubMed, 3 syntheses or guidelines pooled it, 354 citations in OpenAlex.
- Fluoride as a Modifier of Metallome Homeostasis: A Systematic Review of Animal Studies.Basic & clinical pharmacology & toxicology · 2026Pooled it
- Obesity and Its Association With Micronutrient Deficiency Among Mexican Children and Adolescents: A Systematic Review and Meta-analysis.Nutrition reviews · 2026Pooled it
- Effects of total flavonoids of Rhizoma Drynariae on biochemical indicators of bone metabolism: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Pooled it
- Can supplements with prebiotic fibres positively influence bone health in type 2 diabetes? Insights from a randomised controlled crossover trial.Archives of osteoporosis · 2025Trial
- Therapeutic efficacy of zoledronic acid combined with calcium and calcitriol in the treatment of senile osteoporosis in elderly patients.Inflammopharmacology · 2025Trial
- Evaluation of calcium and phosphorus elements in the developing human fetal long bone at different trimesters of pregnancy.Anatomy & cell biology · 2026Article
- Micronutrient risk with GLP-1 receptor and dual incretin agonists in obesity: Mechanistic pathways, clinical signals, and a monitoring framework.Obesity pillars · 2026Review
- Phosphorus alleviates age-associated osteoporosis in laying hens by reshaping bone metabolism and modulating cecal microbial communities.Poultry science · 2026Article
- Plant-based macronutrients and micronutrients in combating osteoporosis: research insights and molecular pathways.RSC advances · 2026Review
- Review
- Could Trace Elements be Linked to Fracture Healing Acceleration in Traumatic Brain Injury-related Skeletal Polytrauma?Biological trace element research · 2026Article
- Sensory acceptance of flavoured high-calcium tempeh (TempeCal) chips among women of reproductive age.Scientific reports · 2026Article
- Impact of the COVID-19 pandemic on growth, nutrition and immune function in infants and toddlers.Public health nutrition · 2026Article
- Directional bone matrix mineralization in the CAM assay is governed by vascular integration and matrix remodeling.bioRxiv : the preprint server for biology · 2026Article
- Association between blood lead levels and body composition parameters in middle-aged pre- and postmenopausal women.BMC public health · 2026Article
- Chemical Composition, Bioactive Constituents, and Functional Value of Chinese Palm Fruit: Processing Effects, Nutritional Significance, and Industrial Prospects-A Review.Foods (Basel, Switzerland) · 2026Review
- Association of the vitamin D metabolite ratio with bone turnover markers and changes in volumetric BMD.JBMR plus · 2026Article
- Using Citric-Acid-Based Anodization to Form Magnesium-Doped Carbonated Apatite-Containing Oxides on Solid and 3D-Printed Titanium Substrates.Journal of functional biomaterials · 2026Article
- Therapeutic efficacy of Curcuma longa leaf extract in experimental models of arthritis.Inflammopharmacology · 2026Article
- Ecotoxicological effects of lead in ducks and geese.Veterinary research communications · 2026Review
94 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium-phosphorus homeostasis. The bone metabolism and tissue properties are influenced by trace elements that may act either indirectly through the regulation of macromineral metabolism, or directly by affecting osteoblast and osteoclast proliferation or activity, or through becoming part of the bone mineral matrix. This study analyzes the skeletal impact of macroelements (calcium, magnesium, phosphorus), microelements (fluorine), and heavy metals (lead), and discusses the concentration of each of these elements in the various bone tissues.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.