Evidence map›Paper›PMID 33800897›Full record

ArticleInternational journal of molecular sciences2021

Magic Peptide: Unique Properties of the LRR11 Peptide in the Activation of Leukotriene Synthesis in Human Neutrophils.

Galina M Viryasova, Ekaterina A Golenkina, Tibor Hianik, Nataliya V Soshnikova, Nina G Dolinnaya, Tatjana V Gaponova, Yulia M Romanova, Galina F Sud'ina

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Galina M ViryasovaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Ekaterina A GolenkinaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.ORCID 0000-0002-5718-9698
Tibor HianikDepartment of Nuclear Physics and Biophysics, Comenius University, Mlynska dolina F1, 842 48 Bratislava, Slovakia.ORCID 0000-0002-5906-0548
Nataliya V SoshnikovaInstitute of Gene Biology, Department of Eukaryotic Transcription Factors, Russian Academy of Sciences, Vavilov Str. 34/5, 119334 Moscow, Russia.
Nina G DolinnayaDepartment of Chemistry, Lomonosov Moscow State University, 119234 Moscow, Russia.ORCID 0000-0003-1780-813X
Tatjana V GaponovaNational Research Center for Hematology, Russia Federation Ministry of Public Health, 125167 Moscow, Russia.
Yulia M RomanovaGamaleya National Research Centre of Epidemiology and Microbiology, 123098 Moscow, Russia.
Galina F Sud'inaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.ORCID 0000-0001-7711-3167
Lomonosov Moscow State University · RUComenius University Bratislava · SKInstitute of Gene Biology · RU

Funding

Russian Foundation for Basic Research 20-04-00816Science Grant Agency VEGA 1/0419/20
6 · The paper itself

Abstract

Neutrophil-mediated innate host defense mechanisms include pathogen elimination through bacterial phagocytosis, which activates the 5-lipoxygenase (5-LOX) product synthesis. Here, we studied the effect of synthetic oligodeoxyribonucleotides (ODNs), which mimic the receptor-recognized sites of bacterial (CpG-ODNs) and genomic (G-rich ODNs) DNAs released from the inflammatory area, on the neutrophil functions after cell stimulation with

Indexed as

Arachidonate 5-LipoxygenaseBenzamidesCalciumCpG IslandsEnzyme ActivationHumansKineticsLeukotrienesNeutrophilsOligodeoxyribonucleotidesOpsonin ProteinsPeptide FragmentsReactive Oxygen SpeciesReceptor for Advanced Glycation End ProductsSalmonella typhimuriumToll-Like Receptor 9AGER protein, humanALOX5 protein, humanArachidonate 5-LipoxygenaseBenzamidesCalciumFPS-ZM1LeukotrienesOligodeoxyribonucleotidesOpsonin ProteinsPeptide FragmentsReactive Oxygen SpeciesReceptor for Advanced Glycation End ProductsTLR9 protein, humanToll-Like Receptor 9acoustic methodLangmuir isothermleukotrieneLRR11neutrophiloligodeoxyribonucleotides

Identifiers

PMID33800897
PMCPMC7961786
OpenAlexW3135785256

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.