Evidence mapPaperPMID 33801029Full record

ArticleNutrients2021

Associations between Circulating Markers of Cholesterol Homeostasis and Macrovascular Events among Patients Undergoing Hemodialysis.

Wen-Chin Lee, Wei-Hung Kuo, Sin-Hua Moi, Barry Chiu, Jin-Bor Chen, Cheng-Hong Yang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Wen-Chin LeeDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.ORCID 0000-0001-6172-1483
Wei-Hung KuoDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Sin-Hua MoiCenter of Cancer Program Development, E-Da Cancer Hospital, I-Shou University, Kaohsiung 84001, Taiwan.ORCID 0000-0002-4082-1909
Barry ChiuDepartment of Epidemiology, Brown University School of Public Health, Providence, RI 02903, USA.
Jin-Bor ChenDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.ORCID 0000-0003-4007-1455
Cheng-Hong YangDepartment of Electronic Engineering, National Kaohsiung University of Science and Technology, Kaohsiung 80778, Taiwan.ORCID 0000-0002-2741-0072
Chang Gung University · TWBrown University · USI-Shou University · TWKaohsiung Medical University · TW

Funding

Kaohsiung Chang Gung Memorial Hospital CMRPG8K0541
6 · The paper itself

Abstract

Current strategies targeting serum cholesterol bring limited benefits to mortality and macrovascular events prevention among hemodialysis patients. Direct measurements and analysis on circulating markers of cholesterol homeostasis could be promising solutions to this bottleneck. We prospectively enrolled 90 maintenance hemodialysis patients and 9 healthy controls in 2019 for 1 year. We measured circulating desmosterol and lathosterol as markers for cholesterol synthesis and campesterol and sitosterol for cholesterol absorption. At baseline, hemodialysis patients showed higher levels of campesterol (

Indexed as

HomeostasisRenal DialysisAgedBiomarkersCholesterolFemaleHumansLogistic ModelsMaleMiddle AgedOdds RatioRegression AnalysisSitosterolsTriglyceridesBiomarkersCholesterolgamma-sitosterollathosterolSitosterolsTriglyceridescholesterol homeostasishemodialysismacrovascular eventsmortality

Identifiers

PMID33801029
PMCPMC8004048
OpenAlexW3136423128

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.