Evidence mapPaperPMID 33801539Full record

ReviewInternational journal of molecular sciences2021

Survey of MRI Usefulness for the Clinical Assessment of Bone Microstructure.

Enrico Soldati, Francesca Rossi, Jerome Vicente, Daphne Guenoun, Martine Pithioux, Stefano Iotti, Emil Malucelli, David Bendahan

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Trabecular bone score in adults with type 1 diabetes: a meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
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  3. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Enrico SoldatiCRMBM, CNRS, Aix Marseille University, 13385 Marseille, France.ORCID 0000-0003-2818-7500
Francesca RossiDepartment of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.
Jerome VicenteIUSTI, CNRS, Aix Marseille University, 13013 Marseille, France.
Daphne GuenounISM, CNRS, Aix Marseille University, 13288 Marseille, France.
Martine PithiouxISM, CNRS, Aix Marseille University, 13288 Marseille, France.ORCID 0000-0001-5283-3504
Stefano IottiDepartment of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-1426-6400
Emil MalucelliDepartment of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-1077-0098
David BendahanCRMBM, CNRS, Aix Marseille University, 13385 Marseille, France.

Funding

Horizon 2020 Marie Skodowska-Curie grant 713750
6 · The paper itself

Abstract

Bone microarchitecture has been shown to provide useful information regarding the evaluation of skeleton quality with an added value to areal bone mineral density, which can be used for the diagnosis of several bone diseases. Bone mineral density estimated from dual-energy X-ray absorptiometry (DXA) has shown to be a limited tool to identify patients' risk stratification and therapy delivery. Magnetic resonance imaging (MRI) has been proposed as another technique to assess bone quality and fracture risk by evaluating the bone structure and microarchitecture. To date, MRI is the only completely non-invasive and non-ionizing imaging modality that can assess both cortical and trabecular bone in vivo. In this review article, we reported a survey regarding the clinically relevant information MRI could provide for the assessment of the inner trabecular morphology of different bone segments. The last section will be devoted to the upcoming MRI applications (MR spectroscopy and chemical shift encoding MRI, solid state MRI and quantitative susceptibility mapping), which could provide additional biomarkers for the assessment of bone microarchitecture.

Indexed as

AnimalsBone and BonesBone DensityFractures, BoneHumansImage Processing, Computer-AssistedMagnetic Resonance Imagingbone microarchitecturebone morphologybone qualityMRI

Identifiers

PMID33801539
PMCPMC7958958

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.