Evidence map›Paper›PMID 33804203›Full record

ArticleInternational journal of molecular sciences2021

Antiosteoarthritic Effect of Morroniside in Chondrocyte Inflammation and Destabilization of Medial Meniscus-Induced Mouse Model.

Eunkuk Park, Chang Gun Lee, Seong Jae Han, Seung Hee Yun, Seokjin Hwang, Hyoju Jeon, Jeonghyun Kim, Chun Whan Choi, Siyoung Yang, Seon-Yong Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Eunkuk ParkDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-1928-5531
Chang Gun LeeDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-2031-0802
Seong Jae HanDepartment of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon 16499, Korea.
Seung Hee YunDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.
Seokjin HwangDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.
Hyoju JeonDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.
Jeonghyun KimDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-9497-9779
Chun Whan ChoiNatural Products Research Institute, Gyeonggi Institute of Science & Technology Promotion, Suwon 16229, Korea.
Siyoung YangDepartment of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-6374-0140
Seon-Yong JeongDepartment of Medical Genetics, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0002-0625-3530
Ajou University · KRGyeonggi Research Institute · KR

Funding

National Research Foundation of Korea (NRF) grant 2020R1I1A1A01072353Technology development Program of the Ministry of SMEs and Startups S2910765
6 · The paper itself

Abstract

Osteoarthritis (OA) is a common degenerative disease that results in joint inflammation as well as pain and stiffness. A previous study has reported that

Indexed as

AnimalsCartilage, ArticularChondrocytesCornusCyclooxygenase 2DinoprostoneDisease Models, AnimalGene Expression RegulationGlycosidesHumansInflammationInterleukin-1betaMatrix Metalloproteinase 13Matrix Metalloproteinase 3Menisci, TibialMiceCyclooxygenase 2DinoprostoneGlycosidesIL1B protein, mouseInterleukin-1betaMatrix Metalloproteinase 13Matrix Metalloproteinase 3morronisidePlant ExtractsPtgs2 protein, mousealternative medicineanti-inflammatory effectmorronisideosteoarthritis

Identifiers

PMID33804203
PMCPMC7999654
OpenAlexW3136129197

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.