Evidence map›Paper›PMID 33806545›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Harnessing the Benefits of Endogenous Hydrogen Sulfide to Reduce Cardiovascular Disease.

Kevin M Casin, John W Calvert

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Utility of NO and HNitric oxide : biology and chemistry · 2022
    Review
  6. Article
  7. Review
  8. The Impact of HAntioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kevin M CasinCarlyle Fraser Heart Center, Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA.
John W CalvertCarlyle Fraser Heart Center, Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA.
Emory University · US

Funding

Targeting the orphan nuclear receptor LRH-1 with small moleculesR01DK115213 · NIDDK · EMORY UNIVERSITY · PI John Winter Calvert, Eric A Ortlund · 2017 to 2026
$4.6M
Novel Insights into Ischemic-Induced Cardiac RemodelingR01HL136915 · NHLBI · EMORY UNIVERSITY · PI CALVERT, JOHN WINTER, LI, LIAN · 2018 to 2021
$1.8M
NHLBI NIH HHS R01 HL136915NIH HHS R01DK115213NIH HHS R01HL136915NIH HHS R01HL136915-02S1
6 · The paper itself

Abstract

Cardiovascular disease is the leading cause of death in the U.S. While various studies have shown the beneficial impact of exogenous hydrogen sulfide (H

Indexed as

cardiovascular diseasediabetic cardiomyopathyexercisefastingheartheart failurehydrogen sulfidemetabolism

Identifiers

PMID33806545
PMCPMC8000539
OpenAlexW3135650065

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.