Evidence map›Paper›PMID 33807102›Full record

Trial reportNutrients2021

The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults.

Nicholas Edward Phillips, Julie Mareschal, Nathalie Schwab, Emily N C Manoogian, Sylvie Borloz, Giada Ostinelli, Aude Gauthier-Jaques, Sylvie Umwali, Elena Gonzalez Rodriguez, Daniel Aeberli and 5 more

2 registry-linked trialsAbstract readRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 72 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03241121 nacompletednot on this map

Study of Eating Patterns With a Smartphone App and the Metabolic Effects of Time Restricted Feeding (TRF) in the Metabolic Syndrome - An Open-label Randomized Controlled Trial of TRF vs Regular Dietary Advices

TypeinterventionalSponsorUniversity of Lausanne HospitalsRan2017 to 2022Enrolled235ConditionsEating Behavior, Metabolic Syndrome, Obesity, DyslipidemiasArmsTime restricted feeding, Regular dietary advices, Eating patterns
NCT07262593 naterminatednot on this mapstarted 2024, after this paper: background citation

Family-Based Meal Timing for Cancer Prevention Among Native Hawaiian and Other Pacific Islanders: FAMTIME

TypeinterventionalSponsorUniversity of UtahRan2024 to 2024Enrolled2ConditionsCancer PreventionArmsTime Restricted Eating (TRE), Medically Tailored Meals (MTM)
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nicholas Edward PhillipsInstitute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.ORCID 0000-0001-7629-9721
Julie MareschalService of Endocrinology, Diabetes, Nutrition and Therapeutic Education, Department of Medicine, Geneva University Hospitals (HUG), 1211 Geneva, Switzerland.
Nathalie SchwabService of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Emily N C ManoogianSalk Institute for Biological Sciences, La Jolla, CA 92037, USA.ORCID 0000-0001-9718-9310
Sylvie BorlozService of Paediatrics, Department Woman-Mother-Child, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.ORCID 0000-0002-6199-1413
Giada OstinelliService of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Aude Gauthier-JaquesService of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Sylvie UmwaliService of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Elena Gonzalez RodriguezInterdisciplinary Center for Bone Diseases, Service of Rheumatology, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Daniel AeberliDepartment of Rheumatology and Immunology, Bern University Hospital, Inselspital and University of Bern, 3010 Bern, Switzerland.
Didier HansInterdisciplinary Center for Bone Diseases, Service of Rheumatology, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Satchidananda PandaSalk Institute for Biological Sciences, La Jolla, CA 92037, USA.
Nicolas RodondiDepartment of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, 3010 Bern, Switzerland.
Felix NaefInstitute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Tinh-Hai ColletService of Endocrinology, Diabetes, Nutrition and Therapeutic Education, Department of Medicine, Geneva University Hospitals (HUG), 1211 Geneva, Switzerland.ORCID 0000-0002-3243-1222

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PZ00P3-167826
6 · The paper itself

Abstract

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships between eating duration, unprocessed and processed food consumption and metabolic health. During 4 weeks of observation, 213 adults used a smartphone application to record food and drink consumption, which was annotated for food processing levels following the NOVA classification. Low consumption of unprocessed food and low physical activity showed significant associations with multiple MS components. Second, in a pragmatic randomised controlled trial, we compared the metabolic benefits of 12 h time-restricted eating (TRE) to standard dietary advice (SDA) in 54 adults with an eating duration > 14 h and at least one MS component. After 6 months, those randomised to TRE lost 1.6% of initial body weight (SD 2.9,

Indexed as

Body WeightDietEatingAdolescentAdultAgedBody CompositionDiet TherapyExerciseFast FoodsFemaleHumansMaleMetabolic SyndromeMiddle AgedNutrition Therapydietary adviceeating patternmetabolic syndromeNOVA classificationprocessed foodtime-restricted eatingweight loss

Identifiers

PMID33807102
PMCPMC8004978

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.