Evidence map›Paper›PMID 33807334›Full record

ArticleMetabolites2021

gcProfileMakeR: An R Package for Automatic Classification of Constitutive and Non-Constitutive Metabolites.

Fernando Perez-Sanz, Victoria Ruiz-Hernández, Marta I Terry, Sara Arce-Gallego, Julia Weiss, Pedro J Navarro, Marcos Egea-Cortines

Abstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. The Effect of Post-harvest Conditions inFrontiers in plant science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fernando Perez-SanzInstituto Murciano de Investigaciones Biomédicas El Palmar, 30120 Murcia, Spain.ORCID 0000-0002-8143-7794
Victoria Ruiz-HernándezDepartment of Biosciences, University Salzburg, 5020 Salzburg, Austria.
Marta I TerryGenética Molecular, Instituto de Biotecnología Vegetal, Edificio I+D+I, Plaza del Hospital s/n, Universidad Politécnica de Cartagena, 30202 Cartagena, Spain.
Sara Arce-GallegoVall d'Hebron Institute of Oncology, 08035 Barcelona, Spain.
Julia WeissGenética Molecular, Instituto de Biotecnología Vegetal, Edificio I+D+I, Plaza del Hospital s/n, Universidad Politécnica de Cartagena, 30202 Cartagena, Spain.ORCID 0000-0003-2432-2613
Pedro J NavarroDSIE Cuartel de Antiguones, Plaza del Hospital s/n, Universidad Politécnica de Cartagena, 30202 Cartagena, Spain.ORCID 0000-0001-8367-2934
Marcos Egea-CortinesGenética Molecular, Instituto de Biotecnología Vegetal, Edificio I+D+I, Plaza del Hospital s/n, Universidad Politécnica de Cartagena, 30202 Cartagena, Spain.ORCID 0000-0003-4693-9948

Funding

Ministerio de Ciencia, Innovación y Universidades BFU2017-88300-C2-1RMinisterio de Ciencia, Innovación y Universidades BFU2017-88300-C2-2RMinisterio de Educación, Cultura y Deporte FPU13/03606
6 · The paper itself

Abstract

Metabolomes comprise constitutive and non-constitutive metabolites produced due to physiological, genetic or environmental effects. However, finding constitutive metabolites and non-constitutive metabolites in large datasets is technically challenging. We developed gcProfileMakeR, an R package using standard Excel output files from an Agilent Chemstation GC-MS for automatic data analysis using CAS numbers. gcProfileMakeR has two filters for data preprocessing removing contaminants and low-quality peaks. The first function NormalizeWithinFiles, samples assigning retention times to CAS. The second function NormalizeBetweenFiles, reaches a consensus between files where compounds in close retention times are grouped together. The third function getGroups, establishes what is considered as Constitutive Profile, Non-constitutive by Frequency i.e., not present in all samples and Non-constitutive by Quality. Results can be plotted with the plotGroup function. We used it to analyse floral scent emissions in four snapdragon genotypes. These included a wild type,

Indexed as

automatic classificationcircadian clockconstitutive metabolomefloral organ identitygcProfileMakeRmachine learningnon-constitutive metabolomeR package

Identifiers

PMID33807334
PMCPMC8065537

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.