Evidence mapPaperPMID 33807902Full record

ArticleInternational journal of molecular sciences2021

Impact of Different Physical Exercises on the Expression of Autophagy Markers in Mice.

Ana P Pinto, Alisson L da Rocha, Bruno B Marafon, Rafael L Rovina, Vitor R Muñoz, Lilian E C M da Silva, José R Pauli, Leandro P de Moura, Dennys E Cintra, Eduardo R Ropelle and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  3. Review
  4. Review
  5. Review
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  7. Review
  8. Review
  9. Review
  10. Article
  11. Autophagy in Heart Failure: Insights into Mechanisms and Therapeutic Implications.Journal of cardiovascular development and disease · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Reviewing physical exercise in non-obese diabetic Goto-Kakizaki rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ana P PintoPostgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto 14040-907, Brazil.ORCID 0000-0002-9139-6746
Alisson L da RochaPostgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto 14040-907, Brazil.
Bruno B MarafonSchool of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto 14040-907, Brazil.
Rafael L RovinaSchool of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto 14040-907, Brazil.
Vitor R MuñozLaboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Rua Pedro Zacarias, 1300, Limeira 13484-350, Brazil.ORCID 0000-0003-4280-6558
Lilian E C M da SilvaDepartment of Ophthalmology, Otorhinolaryngology, and Head and Neck Surgery, School of Medicine of Ribeirão Preto, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto 14040-907, Brazil.
José R PauliLaboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Rua Pedro Zacarias, 1300, Limeira 13484-350, Brazil.
Leandro P de MouraLaboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Rua Pedro Zacarias, 1300, Limeira 13484-350, Brazil.ORCID 0000-0003-3211-1058
Dennys E CintraLaboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Rua Pedro Zacarias, 1300, Limeira 13484-350, Brazil.ORCID 0000-0002-7954-5630
Eduardo R RopelleLaboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Rua Pedro Zacarias, 1300, Limeira 13484-350, Brazil.
Adelino S R da SilvaPostgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto 14040-907, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade de Ribeirão Preto · BRUniversidade de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 301279/2019-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/09038-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/12765-2Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/19869-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/10875-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/17058-8
6 · The paper itself

Abstract

Although physical exercise-induced autophagy activation has been considered a therapeutic target to enhance tissue health and extend lifespan, the effects of different exercise models on autophagy in specific metabolic tissues are not completely understood. This descriptive investigation compared the acute effects of endurance (END), exhaustive (ET), strength (ST), and concurrent (CC) physical exercise protocols on markers of autophagy, genes, and proteins in the gastrocnemius muscle, heart, and liver of mice. The animals were euthanized immediately (0 h) and six hours (6 h) after the acute exercise for the measurement of glycogen levels, mRNA expression of

Indexed as

AutophagyGene Expression RegulationPhysical Conditioning, AnimalAnimalsBiomarkersMaleMiceMuscle ProteinsMuscle, SkeletalBiomarkersMuscle Proteinsautophagic fluxcolchicinegastrocnemiusheartlivertime course

Identifiers

PMID33807902
PMCPMC7962017
OpenAlexW3135412080

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.