Evidence map›Paper›PMID 33809053›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Baseline and Kinetic Circulating Tumor Cell Counts Are Prognostic Factors in a Prospective Study of Metastatic Colorectal Cancer.

Virgílio Souza E Silva, Emne Ali Abdallah, Angelo Borsarelli Carvalho de Brito, Alexcia Camila Braun, Milena Shizue Tariki, Celso Abdon Lopes de Mello, Vinicius Fernando Calsavara, Rachel Riechelmann, Ludmilla Thomé Domingos Chinen

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
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  6. Review
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Virgílio Souza E SilvaDepartment of Medical Oncology, A.C. Camargo Cancer Center, São Paulo 01509-900, Brazil.ORCID 0000-0001-6108-3362
Emne Ali AbdallahInternational Research Center, A.C. Camargo Cancer Center, São Paulo 01508-010, Brazil.
Angelo Borsarelli Carvalho de BritoDepartment of Medical Oncology, A.C. Camargo Cancer Center, São Paulo 01509-900, Brazil.
Alexcia Camila BraunInternational Research Center, A.C. Camargo Cancer Center, São Paulo 01508-010, Brazil.ORCID 0000-0002-9028-2026
Milena Shizue TarikiDepartment of Medical Oncology, A.C. Camargo Cancer Center, São Paulo 01509-900, Brazil.
Celso Abdon Lopes de MelloDepartment of Medical Oncology, A.C. Camargo Cancer Center, São Paulo 01509-900, Brazil.ORCID 0000-0002-8315-1562
Vinicius Fernando CalsavaraInternational Research Center, A.C. Camargo Cancer Center, São Paulo 01508-010, Brazil.
Rachel RiechelmannDepartment of Medical Oncology, A.C. Camargo Cancer Center, São Paulo 01509-900, Brazil.
Ludmilla Thomé Domingos ChinenInternational Research Center, A.C. Camargo Cancer Center, São Paulo 01508-010, Brazil.
AC Camargo Hospital · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2012/01273-8Ricardo Renzo Brentani Grant 201
6 · The paper itself

Abstract

The discovery of predictive biomarkers in metastatic colorectal cancer (mCRC) is essential to improve clinical outcomes. Recent data suggest a potential role of circulating tumor cells (CTCs) as prognostic indicators. We conducted a follow-on analysis from a prospective study of consecutive patients with mCRC. CTC analysis was conducted at two timepoints: baseline (CTC1; before starting chemotherapy), and two months after starting treatment (CTC2). CTC isolation/quantification were completed by ISET

Indexed as

circulating tumor cellskineticsmetastatic colorectal cancermultidrug resistance protein 1 (MRP-1)prognosis

Identifiers

PMID33809053
PMCPMC7999095
OpenAlexW3137100895

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.