Evidence mapPaperPMID 33809076Full record

ArticleNanomaterials (Basel, Switzerland)2021

Wound Healing Composite Materials of Bacterial Cellulose and Zinc Oxide Nanoparticles with Immobilized Betulin Diphosphate.

Nina Melnikova, Alexander Knyazev, Viktor Nikolskiy, Peter Peretyagin, Kseniia Belyaeva, Natalia Nazarova, Elena Liyaskina, Darina Malygina, Viktor Revin

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nina MelnikovaFaculty of Chemistry, Lobachevsky University, 23/5 Gagarin Av., 603950 Nizhny Novgorod, Russia.ORCID 0000-0003-1335-1048
Alexander KnyazevFaculty of Chemistry, Lobachevsky University, 23/5 Gagarin Av., 603950 Nizhny Novgorod, Russia.ORCID 0000-0002-2880-3484
Viktor NikolskiyNizhni Novgorod Regional Clinical Hospital named after N.A. Semashko, 190 Rodionova str., 603126 Nizhny Novgorod, Russia.
Peter PeretyaginDepartment of Experimental Medicine, Privolzhsky Research Medical University, 10/1 Minin sq., 603950 Nizhny Novgorod, Russia.ORCID 0000-0003-0707-892X
Kseniia BelyaevaDepartment of Experimental Medicine, Privolzhsky Research Medical University, 10/1 Minin sq., 603950 Nizhny Novgorod, Russia.ORCID 0000-0002-1700-0846
Natalia NazarovaDepartment of Biotechnology, Bioengineering and Biochemistry, National Research Ogarev Mordovia State University, 68 Bolshevistskaya str., 430005 Saransk, Russia.
Elena LiyaskinaDepartment of Biotechnology, Bioengineering and Biochemistry, National Research Ogarev Mordovia State University, 68 Bolshevistskaya str., 430005 Saransk, Russia.ORCID 0000-0003-1719-8052
Darina MalyginaDepartment of Pharmaceutical Chemistry, Privolzhsky Research Medical University, 10/1 Minin sq., 603950 Nizhny Novgorod, Russia.
Viktor RevinDepartment of Biotechnology, Bioengineering and Biochemistry, National Research Ogarev Mordovia State University, 68 Bolshevistskaya str., 430005 Saransk, Russia.ORCID 0000-0001-6542-2667
National Research Mordovia State University · RUPrivolzhsky Research Medical University · RUN. I. Lobachevsky State University of Nizhny Novgorod · RUNizhny Novgorod Regional Clinical Hospital named after Semashko · RU

Funding

Ministry of Science and Higher Education of the Russian Federation FZRS-2020-0003Russian Foundation for Basic Research 19-515-80002/19
6 · The paper itself

Abstract

A design of new nanocomposites of bacterial cellulose (BC) and betulin diphosphate (BDP) pre-impregnated into the surface of zinc oxide nanoparticles (ZnO NPs) for the production of wound dressings is proposed. The sizes of crystalline BC and ZnO NPs (5-25%) corresponded to 5-6 nm and 10-18 nm, respectively (powder X-ray diffractometry (PXRD), Fourier-infrared (FTIR), ultraviolet (UV), atomic absorption (AAS) and photoluminescence (PL) spectroscopies). The biological activity of the wound dressings "BC-ZnO NPs-BDP" was investigated in rats using a burn wound model. Morpho-histological studies have shown that more intensive healing was observed during treatment with hydrophilic nanocomposites than the oleophilic standard (ZnO NPs-BDP oleogel;

Indexed as

antioxidant propertiesbacterial cellulosebetulin diphosphateburnswound dressingszinc oxide nanoparticles

Identifiers

PMID33809076
PMCPMC8000300
OpenAlexW3137049242

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.