Evidence map›Paper›PMID 33809500›Full record

ReviewAnimals : an open access journal from MDPI2021

Key Genes Regulating Skeletal Muscle Development and Growth in Farm Animals.

Mohammadreza Mohammadabadi, Farhad Bordbar, Just Jensen, Min Du, Wei Guo

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 1 pooled it
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 1 synthesis or guideline pooled it, 238 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Transcriptome Sequencing of LYPLA1 Gene Overexpression and Interference.Animals : an open access journal from MDPI · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. PorcineAnimals : an open access journal from MDPI · 2026
    Article
  16. Article
  17. Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
    Article
  18. Article
  19. Genome-wide detection of copy number variations in indigenous Red Sindhi cattle using ddRAD sequencing.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  20. The Function of the Lysophospholipase 1 (Animals : an open access journal from MDPI · 2025
    Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Mohammadreza MohammadabadiDepartment of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman 77951, Iran.ORCID 0000-0002-1268-3043
Farhad BordbarDepartment of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman 77951, Iran.ORCID 0000-0002-2081-930X
Just JensenCenter for Quantitative Genetics and Genomics, Aarhus University, 8210 Aarhus, Denmark.ORCID 0000-0003-3291-8468
Min DuWashington Center for Muscle Biology, Department of Animal Sciences, Washington State University, Pullman, WA 99163, USA.
Wei GuoMuscle Biology and Animal Biologics, Animal and Dairy Science, University of Wisconsin-Madison, Madison, WI 53558, USA.
Shahid Bahonar University of Kerman · IRAarhus University · DKUniversity of Wisconsin–Madison · USWashington Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Farm-animal species play crucial roles in satisfying demands for meat on a global scale, and they are genetically being developed to enhance the efficiency of meat production. In particular, one of the important breeders' aims is to increase skeletal muscle growth in farm animals. The enhancement of muscle development and growth is crucial to meet consumers' demands regarding meat quality. Fetal skeletal muscle development involves myogenesis (with myoblast proliferation, differentiation, and fusion), fibrogenesis, and adipogenesis. Typically, myogenesis is regulated by a convoluted network of intrinsic and extrinsic factors monitored by myogenic regulatory factor genes in two or three phases, as well as genes that code for kinases. Marker-assisted selection relies on candidate genes related positively or negatively to muscle development and can be a strong supplement to classical selection strategies in farm animals. This comprehensive review covers important (candidate) genes that regulate muscle development and growth in farm animals (cattle, sheep, chicken, and pig). The identification of these genes is an important step toward the goal of increasing meat yields and improves meat quality.

Indexed as

adipogenesiscandidate genemeat yieldmuscle developmentmyogenesis

Identifiers

PMID33809500
PMCPMC7999090
OpenAlexW3136572131

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.