ReviewHealthcare (Basel, Switzerland)2021
Perioperative Pain Management and Opioid Stewardship: A Practical Guide.
Review in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06970704 (Erector Spinae Plane Block Combined With General Anesthesia Versus General Anesthesia Alone in Spine Surgeries for Postoperative Pain, A Randomized Controlled Trial), which is not on this map. Cited by 89 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Erector Spinae Plane Block Combined With General Anesthesia Versus General Anesthesia Alone in Spine Surgeries for Postoperative Pain, A Randomized Controlled Trial
Who cites it
89 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Intercostal Nerve Cryoablation Therapy in Thoracic and Cardiac Surgery for Postoperative Pain Management: A Systematic Review and Meta-Analysis.Interdisciplinary cardiovascular and thoracic surgery · 2026Pooled it
- Systematic review on postoperative opioid use and other outcomes after lobectomy for lung cancer in the U.S.Future oncology (London, England) · 2025Pooled it
- Effect of pharmacist care on clinical outcomes and therapy optimization in perioperative settings: A systematic review.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2024Pooled it
- Peripheral Nerve Stimulation in Postoperative Analgesia: A Narrative Review.Current pain and headache reports · 2024Pooled it
- Effects of transcutaneous electrical nerve stimulation in postoperative total knee arthroplasty pain and intravenous analgesic requirement.Scientific reports · 2026Trial
- Memantine as a pain management strategy post-total knee arthroplasty: a randomized controlled trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Trial
- The Effect of Intraoperative Infusion of Different Doses of Esketamine on the Quality of Recovery in Elderly Patients Undergoing Knee Arthroplasty.Drug design, development and therapy · 2026Trial
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- Perioperative use of ketamine infusion versus dexmedetomidine infusion for analgesia in obese patients undergoing bariatric surgery: a double-blinded three-armed randomized controlled trial.BMC anesthesiology · 2023Trial
- Adults' experiences of perioperative opioid use: a mixed-methods study.Pain reports · 2026Article
- Effect of Intravenous Magnesium on Postoperative Pain and Analgesic Outcomes in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Pharmaceuticals (Basel, Switzerland) · 2026Review
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- Article
- Cymbopogon proximus essential oil promotes wound healing and attenuates inflammation through mechanisms supported by network pharmacology and molecular docking.Scientific reports · 2026Article
- Ultrasound-Guided Percutaneous Electrical Nerve Stimulation (PENS) as an Adjunct to a Multimodal Physical Therapy Program for Postoperative Shoulder Pain: A Randomized Clinical Trial.Healthcare (Basel, Switzerland) · 2026Article
- Impact of intercostal nerve cryoablation on opioid use in pleural mesothelioma surgery: results from a high-volume integrated regional center.Journal of thoracic disease · 2026Article
- Article
- Propensity Score-Matched Comparison of Ultrasound-Guided Versus Open Carpal Tunnel Release: Three-Month Outcomes From the MISSION Registry.Journal of hand surgery global online · 2026Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surgical procedures are key drivers of pain development and opioid utilization globally. Various organizations have generated guidance on postoperative pain management, enhanced recovery strategies, multimodal analgesic and anesthetic techniques, and postoperative opioid prescribing. Still, comprehensive integration of these recommendations into standard practice at the institutional level remains elusive, and persistent postoperative pain and opioid use pose significant societal burdens. The multitude of guidance publications, many different healthcare providers involved in executing them, evolution of surgical technique, and complexities of perioperative care transitions all represent challenges to process improvement. This review seeks to summarize and integrate key recommendations into a "roadmap" for institutional adoption of perioperative analgesic and opioid optimization strategies. We present a brief review of applicable statistics and definitions as impetus for prioritizing both analgesia and opioid exposure in surgical quality improvement. We then review recommended modalities at each phase of perioperative care. We showcase the value of interprofessional collaboration in implementing and sustaining perioperative performance measures related to pain management and analgesic exposure, including those from the patient perspective. Surgery centers across the globe should adopt an integrated, collaborative approach to the twin goals of optimal pain management and opioid stewardship across the care continuum.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.