Evidence map›Paper›PMID 33810482›Full record

ArticleInternational journal of molecular sciences2021

Identification of a Novel Cis-Acting Regulator of HIV-1 Genome Packaging.

Sayuri Sakuragi, Osamu Kotani, Masaru Yokoyama, Tatsuo Shioda, Hironori Sato, Jun-Ichi Sakuragi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Viruses · 2022
    Article
  2. Biophysical Study of the Structure, Dynamics, and Function of Nucleic Acids.International journal of molecular sciences · 2022
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sayuri SakuragiDepartment of Viral Infections, Research Institute for Microbial Diseases, Osaka 565-0871, Japan.
Osamu KotaniPathogen Genomics Center, National Institute for Infectious Diseases, Tokyo 208-0011, Japan.
Masaru YokoyamaPathogen Genomics Center, National Institute for Infectious Diseases, Tokyo 208-0011, Japan.ORCID 0000-0003-1641-0365
Tatsuo ShiodaDepartment of Viral Infections, Research Institute for Microbial Diseases, Osaka 565-0871, Japan.ORCID 0000-0002-3439-8331
Hironori SatoPathogen Genomics Center, National Institute for Infectious Diseases, Tokyo 208-0011, Japan.
Jun-Ichi SakuragiDepartment of Viral Infections, Research Institute for Microbial Diseases, Osaka 565-0871, Japan.ORCID 0000-0003-1877-4680
National Institute of Infectious Diseases · JPMicrobial Chemistry Research Foundation · JPKanagawa Prefectural Institute of Public Health · JP

Funding

The Japan Agency for Medical Research and Development, AMED Research Program on HIV/AIDS: JP18fk0410004 and JP20fk0410027
6 · The paper itself

Abstract

Human immunodeficiency virus type 1 (HIV-1) uptakes homo-dimerized viral RNA genome into its own particle. A cis-acting viral RNA segment responsible for this event, termed

Indexed as

Genome, ViralHIV-1DimerizationGenetic VariationHEK293 CellsHumansHydrogen BondingMolecular Dynamics SimulationNucleic Acid ConformationNucleocapsid ProteinsNucleotidesProtein BindingProtein FoldingRNA, ViralTransfectionVirus AssemblyNucleocapsid ProteinsNucleotidesRNA, Viralgenome packagingHIV-1hydrogen-bond networksmolecular dynamics simulationpsi RNARNA dimerizationRNA foldstructural dynamicsstructure and function

Identifiers

PMID33810482
PMCPMC8036536
OpenAlexW3143594635

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.