Evidence map›Paper›PMID 33816632›Full record

Trial reportBioMed research international2021

Association between Tumor Prognosis Marker Visfatin and Proinflammatory Cytokines in Hypertensive Patients.

Ramya Parimelazhagan, Dhamodharan Umapathy, Inmozhi Ramu Sivakamasundari, Subramaniam Sethupathy, Daoud Ali, Ramkumar Kunka Mohanram, Nalini Namasivayan

RetractedOpen access · hybridAbstract readClinical TrialRetracted Publication
In one paragraph

Trial report in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Pre-procedural high serum visfatin and tumor necrosis factor-α might predict recurrent atrial fibrillation after catheter ablation.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Article
  3. Review
  4. Association of Ellis Class 2 fracture in 13-17 years old children.Journal of advanced pharmaceutical technology & research · 2022
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ramya ParimelazhaganDepartment of Biochemistry, Faculty of Medicine, Rajah Muthiah Medical College and Hospital (RMMCH), Annamalai University, Annamalainagar 608002, India.
Dhamodharan UmapathyDepartment of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai 600 077, India.ORCID https://orcid.org/0000-0002-5281-1070
Inmozhi Ramu SivakamasundariDepartment of Biochemistry, Faculty of Medicine, Rajah Muthiah Medical College and Hospital (RMMCH), Annamalai University, Annamalainagar 608002, India.
Subramaniam SethupathyDepartment of Biochemistry, Faculty of Medicine, Rajah Muthiah Medical College and Hospital (RMMCH), Annamalai University, Annamalainagar 608002, India.
Daoud AliDepartment of Zoology, College of Science King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Ramkumar Kunka MohanramSRM Research Institute, SRM Institute of Science and Technology, Kattankulathur 603203, India.ORCID https://orcid.org/0000-0001-5450-902X
Nalini NamasivayanDepartment of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar 608002, India.ORCID https://orcid.org/0000-0003-3877-0900
Annamalai University · INKing Saud University · SASaveetha University · INSRM Institute of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visfatin has been reported as a risk factor and a potential diagnostic marker in cancer. It is an adipokine, secreted by visceral fat and associated with the pathogenesis of arterial hypertension. We investigated the circulatory levels of visfatin in hypertensive patients with hypertriglyceridemia, which are the risk factors for various cancers and its association with proinflammatory cytokines. A total of 81 (male/female: 33/48) subjects with or without hypertension were enrolled for this study. Group 1 was normotensive, Group 2 hypertensive, and Group 3 with hypertension with hypertriglyceridemia. Data on anthropometric and biochemical data were recorded. Plasma visfatin levels were measured using an ELISA kit. The plasma inflammatory cytokines were estimated using a multiplex bead-based assay. The results revealed that the hypertension with hypertriglyceridemia group has the highest levels of visfatin compared to the hypertension and control groups with a significant difference (

Indexed as

Blood PressureHypertensionHypertriglyceridemiaAdultBiomarkers, TumorCross-Sectional StudiesCytokinesFemaleHumansMaleMiddle AgedNicotinamide PhosphoribosyltransferaseBiomarkers, TumorCytokinesNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, human

Identifiers

PMID33816632
PMCPMC7990525
OpenAlexW3136395773

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.