Evidence map›Paper›PMID 33820937›Full record

ArticleScientific reports2021

The effect of coronary slow flow on left atrial structure and function.

Zhiyuan Shui, Yunzhi Wang, Mingxue Sun, Yiqun Gao, Shunji Liang, Yiran Wang, Xiaomei Wang, Qin Yu, Shulong Zhang, Li Liu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Coronary Slow-Flow Syndrome: A Review on Natural History of Disease and Best Practices.Research in heart yield and translational medicine · 2025
    Review
  5. Article
  6. Association of central arterial stiffness with atrial myopathy: the Atherosclerosis Risk in Communities (ARIC) study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  7. The predictors of coronary slow flow in patients undergoing coronary angiography.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Article
  8. Association of Left Atrial Function With Incident Chronic Kidney Disease in Older Adults.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zhiyuan ShuiDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China.
Yunzhi WangDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China.
Mingxue SunDepartment of Cardiology, The People's Hospital of Sanya City, Sanya, Hainan Province, China.
Yiqun GaoDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China.
Shunji LiangDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China.
Yiran WangDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China.
Xiaomei WangDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China.
Qin YuDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China.
Shulong ZhangDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China. zhangshulongmd@sina.com.
Li LiuDepartment of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 620061, Liaoning Province, China. lbeilliun@yahoo.com.
Affiliated Zhongshan Hospital of Dalian University · CNSanya Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronary slow flow phenomenon (CSFP) is common in coronary angiography, however its impact on left atrial (LA) function is still controversial. This study aims to evaluate the LA structure and function of patients with CSFP using two-dimensional speckle tracking echocardiography (2D-STE). Consecutive patients scheduled for coronary angiography from January 2016 to September 2017 were enrolled in this study. Patients' demographic data, clinical histories, laboratory and angiographic findings were collected and recorded. Diagnostic criteria for CSFP is based on Beltrame et al. proposed in 2012. Meanwhile 139 patients who have no significant stenosis (≤ 40%) and normal blood flow were selected as control. All patients received an echocardiographic examination 24 h before coronary angiography. LA structure and function were measured with echocardiography and 2D-STE. Our results showed that among the 1,954 patients who had received coronary angiography, 512 patients were included in the analysis after the exclusion criteria was implemented. Of those, 101 patients met the CSFP criteria (5.5%). CSFP is mainly seen in LAD (~ 70%). There was no statistical difference in baseline characteristics between the CSFP group and control group, except for a higher proportion of smokers in the CSFP group (P = 0.001). The percentage of monocytes is an independent risk factor for the occurrence of CSFP (P = 0.036) after binary logistic regression analysis. The LA global longitudinal strain (LA-GLS, represents reservoir functions) decreased and LA strain rate at late diastole (LA-SRa, represents booster function) increased in patients with CSFP compared to the control group (P < 0.05). Correlation test of continuous variables by Pearson test suggested that LA-GLS was negatively correlated with TIMI frame count (TFC). We concluded that the percentage of monocytes is an independent risk factor for the CSFP; the LA reservoir and booster functions were impaired in patients with CSFP; LA-GLS is negatively correlated with TFC.

Indexed as

Atrial Function, LeftCase-Control StudiesCoronary AngiographyCoronary CirculationElectrocardiographyFemaleHeart AtriaHumansLogistic ModelsMaleMiddle AgedNo-Reflow Phenomenon

Identifiers

PMID33820937
PMCPMC8021584
OpenAlexW3145037237

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.