Evidence map›Paper›PMID 33824247›Full record

ArticleJournal of biomedical research2020

Triclosan inhibits the activation of human periodontal ligament fibroblasts induced by lipopolysaccharide from

Wei Shu, Yanman Zhang, Chen Zhang, Qiang You, Hong Zhou, Shuang Wen

Open access · diamondAbstract read
In one paragraph

Article in Journal of biomedical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Triclosan: A Small Molecule with Controversial Roles.Antibiotics (Basel, Switzerland) · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Wei ShuDepartment of Immunology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Yanman ZhangDepartment of Immunology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Chen ZhangDepartment of Biotherapeutics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China.
Qiang YouDepartment of Biotherapeutics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China.
Hong ZhouDepartment of Immunology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Shuang WenDepartment of Immunology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Second Affiliated Hospital of Nanjing Medical University · CNNanjing Medical University · CNJiangsu Provincial Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is a highly prevalent, chronic, non-specific, and immunologically devastating disease of periodontal tissues, caused by microbial infection. This study aims to examine the efficacy and protective mechanism of triclosan (TCS), a bisphenolic, non-cationic component of oral care products, against periodontal inflammation induced by lipopolysaccharide purified from

Indexed as

heat shock proteinhuman periodontal ligament fibroblastslipopolysaccharidetriclosan

Identifiers

PMID33824247
PMCPMC8193714
OpenAlexW3142651379

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.