Evidence map›Paper›PMID 33825541›Full record

ArticleJournal of biological rhythms2021

Shared Components of the FRQ-Less Oscillator and TOR Pathway Maintain Rhythmicity in

Rosa Eskandari, Lalanthi Ratnayake, Patricia L Lakin-Thomas

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biological rhythms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  4. Time to start taking time seriously: how to investigate unexpected biological rhythms within infectious disease research.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rosa EskandariDepartment of Biology, York University, Toronto, ON, Canada.ORCID 0000-0002-5641-1699
Lalanthi RatnayakeDepartment of Biology, York University, Toronto, ON, Canada.
Patricia L Lakin-ThomasDepartment of Biology, York University, Toronto, ON, Canada.ORCID 0000-0002-0545-9561
York University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular models for the endogenous oscillators that drive circadian rhythms in eukaryotes center on rhythmic transcription/translation of a small number of "clock genes." Although substantial evidence supports the concept that negative and positive transcription/translation feedback loops (TTFLs) are responsible for regulating the expression of these clock genes, certain rhythms in the filamentous fungus

Indexed as

Circadian RhythmNeurospora crassaBiological ClocksFungal ProteinsGene Expression Regulation, FungalMutationFungal Proteinscircadian rhythmFRQFRQ-less oscillatorRagulatorTOR pathway

Identifiers

PMID33825541
PMCPMC8276340
OpenAlexW3150437505

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.