Evidence map›Paper›PMID 33827945›Full record

ArticleJournal of virology2021

Phenotypic and Functional Characteristics of a Novel Influenza Virus Hemagglutinin-Specific Memory NK Cell.

Jian Zheng, Liyan Wen, Hui-Ling Yen, Ming Liu, Yinping Liu, Ooiean Teng, Wing-Fung Wu, Ke Ni, Kowk-Tai Lam, Chunyu Huang and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. An engineered NKp46 antibody for construction of multi-specific NK cell engagers.Protein engineering, design & selection : PEDS · 2024
    Article
  9. Article
  10. Review
  11. Triphasic production of IFNDiscovery immunology · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Jian Zheng *Department of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong jian-zheng-1@uiowa.edu malik@hku.hk wwtu@hku.hk.
Liyan Wen *Department of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Hui-Ling YenSchool of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0003-2493-3609
Ming LiuState Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yinping LiuDepartment of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Ooiean TengSchool of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Wing-Fung WuSchool of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Ke NiDepartment of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Kowk-Tai LamDepartment of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Chunyu HuangDepartment of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Jiashuang YangDepartment of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Yu-Lung LauDepartment of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Stanley PerlmanDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0003-4213-2354
Malik PeirisSchool of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong jian-zheng-1@uiowa.edu malik@hku.hk wwtu@hku.hk.ORCID 0000-0001-8217-5995
Wenwei TuDepartment of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong jian-zheng-1@uiowa.edu malik@hku.hk wwtu@hku.hk.ORCID 0000-0002-6801-8798
University of Hong Kong · HKUniversity of Iowa · USFirst Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune memory represents the most efficient defense against invasion and transmission of infectious pathogens. In contrast to memory T and B cells, the roles of innate immunity in recall responses remain inconclusive. In this study, we identified a novel mouse spleen NK cell subset expressing NKp46 and NKG2A induced by intranasal influenza virus infection. These memory NK cells specifically recognize

Indexed as

Immunologic MemoryAdoptive TransferAnimalsAntigens, LyBenzothiazolesCD8-Positive T-LymphocytesCoculture TechniquesCytotoxicity, ImmunologicDendritic CellsHemagglutinin Glycoproteins, Influenza VirusInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H9N2 SubtypeInterferon-gammaKiller Cells, NaturalMiceMice, Inbred C57BLAntigens, LyBenzothiazolesH1N1 virus hemagglutininHemagglutinin Glycoproteins, Influenza VirusInterferon-gammaKlrc1 protein, mouseNatural Cytotoxicity Triggering Receptor 1Ncr1 protein, mouseNK Cell Lectin-Like Receptor Subfamily CpifithrinToluenecytotoxicitygamma IFNglycosylationhemagglutininimmune memoryinfluenza virusNK

Identifiers

PMID33827945
PMCPMC8316001
OpenAlexW3152208345

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.