SynthesisPancreas2021
Exercise Medicine in the Management of Pancreatic Cancer: A Systematic Review.
Synthesis in Pancreas, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- One out of four patients with pancreatic cancer experience psychological symptoms: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Effects of exercise by type and duration on quality of life in patients with digestive system cancers: A systematic review and network meta-analysis.Journal of sport and health science · 2023Pooled it
- Effects of intensive physiotherapy on Quality of Life (QoL) after pancreatic cancer resection: a randomized controlled trial.BMC cancer · 2022Trial
- Is there a link between fascia and cancer? From potential mechanisms to future treatment options.Frontiers in physiology · 2026Review
- Effects of exercise therapy in patients with pancreatic cancer: A systematic review and meta-analysis.International journal of nursing studies advances · 2025Review
- Impact of sarcopenia and changes in skeletal muscle mass on prognosis of patients with pancreatic ductal adenocarcinoma receiving chemotherapy with first-line gemcitabine and nab-paclitaxel: a prospective study.Journal of gastroenterology · 2025Article
- International perspectives on exercise oncology: current state, challenges, and opportunities for future development.Journal of the National Cancer Institute. Monographs · 2025Article
- Feasibility, safety, and adherence of home-based exercise interventions in people diagnosed with cancer: a systematic review.Journal of cancer survivorship : research and practice · 2025Review
- Can a physical activity program improve functional capacity and fatigue in people with cancer? A retrospective analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Article
- Pancreatic Cancer: The Advanced Practitioner's Role in Early Diagnosis and Management.Journal of the advanced practitioner in oncology · 2024Review
- The effect of pulmonary rehabilitation on quality of life and functional capacity after chemotherapy in patients with small cell lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- A Multiomics Assessment of Preoperative Exercise in Pancreatic Cancer Survivors Receiving Neoadjuvant Therapy: A Case Series.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024Article
- Impact of sarcopenia on recurrent biliary obstruction after EUS-guided biliary drainage in patients with malignant biliary obstruction.International journal of clinical oncology · 2024Article
- Analysis of physical activity levels and influencing factors in cancer survivors after pancreaticoduodenectomy.Frontiers in oncology · 2024Article
- Effects of Exercise Training on Patient-Specific Outcomes in Pancreatic Cancer Patients: A Scoping Review.Cancers · 2023Article
- Exploring the feasibility of a combined exercise program for patients with advanced lung or pancreatic cancer.Asia-Pacific journal of oncology nursing · 2023Article
- Implication of Skeletal Muscle Loss in the Prognosis of Patients with Pancreatic Ductal Adenocarcinoma Receiving Chemotherapy.Internal medicine (Tokyo, Japan) · 2023Article
- Feasibility of delivering supervised exercise training following surgical resection and during adjuvant chemotherapy for pancreatic ductal adenocarcinoma (PRECISE): a case series.BMC sports science, medicine & rehabilitation · 2023Article
- Complementary and Integrative Medicine in Pancreatic Cancer.Current oncology reports · 2023Review
Corrections and comments
- Commented on by
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractThe aim of this study was to examine the health-related effects of exercise in patients with pancreatic cancer (PanCa) through a systematic review of current evidence. Studies were obtained through searching PubMed, Web of Science, PsycINFO, Embase, CINAHL Plus, and Cochrane Library databases with additional hand searches. All intervention-based studies were included if it involved (1) adult patients with PanCa, (2) exercise training, and (3) findings in quality of life, cancer-related fatigue, psychological distress, and physical function. The review protocol was registered in PROSPERO: CRD42020154684. Seven trials described in 9 publications were included consisting of 201 patients with early-stage and advanced PanCa. Participants were required to perform supervised and/or home-based, low- to moderate-intensity resistance and/or aerobic exercise for 12 to 35 weeks or duration of neoadjuvant therapy. There were no exercise-related adverse events with a reported retention rate of 71% to 90% and exercise attendance of 64% to 96%. The programs were consistently associated with improvements in cancer-related fatigue, psychological distress, and physical function, with mixed effects on quality of life. Exercise training seems to be safe and feasible and may have a beneficial effect on various physical and psychological outcomes in patients with PanCa. Further work with rigorous study designs is required to consolidate and advance current findings.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.