Evidence map›Paper›PMID 33848962›Full record

ArticleMedical image analysis2021

A structural enriched functional network: An application to predict brain cognitive performance.

Mansu Kim, Jingxuan Bao, Kefei Liu, Bo-Yong Park, Hyunjin Park, Jae Young Baik, Li Shen

Abstract read
In one paragraph

Article in Medical image analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  16. Identifying imaging genetic associations via regional morphometricity estimation.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mansu KimDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, PA, USA.
Jingxuan BaoSchool of Arts and Sciences, University of Pennsylvania, PA, USA.
Kefei LiuDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, PA, USA.
Bo-Yong ParkMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada.
Hyunjin ParkSchool of Electronic and Electrical Engineering, Sungkyunkwan University, Suwon, South Korea; Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, South Korea.
Jae Young BaikSchool of Arts and Sciences, University of Pennsylvania, PA, USA.
Li ShenDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, PA, USA. Electronic address: Li.Shen@pennmedicine.upenn.edu.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
Biomedical Image Computing and Informatics ClusterS10OD023495 · OD · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2017
$1.9M
Integrative Bioinformatics Approaches to Human Brain Genomics and ConnectomicsR01EB022574 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI SHEN, LI · 2016 to 2019
$1.9M
Informatics Algorithms for Genomic Analysis of Brain Imaging DataR01LM013463 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H., SAYKIN, ANDREW J · 2020 to 2023
$1.4M
NIA NIH HHS U01 AG068057NIBIB NIH HHS R01 EB022574NIH HHS S10 OD023495NIMH NIH HHS U54 MH091657NLM NIH HHS R01 LM013463
6 · The paper itself

Abstract

The structure-function coupling in brain networks has emerged as an important research topic in modern neuroscience. The structural network could provide the backbone of the functional network. The integration of the functional network with structural information can help us better understand functional communication in the brain. This paper proposed a method to accurately estimate the brain functional network enriched by the structural network from diffusion magnetic resonance imaging. First, we adopted a simplex regression model with graph-constrained Elastic Net to construct the functional networks enriched by the structural network. Then, we compared the constructed network characteristics of this approach with several state-of-the-art competing functional network models. Furthermore, we evaluated whether the structural enriched functional network model improves the performance for predicting the cognitive-behavioral outcomes. The experiments have been performed on 218 participants from the Human Connectome Project database. The results demonstrated that our network model improves network consistency and its predictive performance compared with several state-of-the-art competing functional network models.

Indexed as

ConnectomeNerve NetBrainCognitionDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingFunctional networkGraph-constrained elastic netSimplex regressionStructure-function coupling

Identifiers

PMID33848962
PMCPMC8184595

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.