Evidence map›Paper›PMID 33860111›Full record

ArticleNanoImpact2021

STAT6-Dependent Exacerbation of House Dust Mite-Induced Allergic Airway Disease in Mice by Multi-Walled Carbon Nanotubes.

Mark D Ihrie, Katherine S Duke, Kelly A Shipkowski, Dorothy J You, Ho Young Lee, Alexia J Taylor-Just, James C Bonner

Open access · greenAbstract read
In one paragraph

Article in NanoImpact, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mark D IhrieToxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695 U.S.A.
Katherine S DukeToxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695 U.S.A.
Kelly A ShipkowskiToxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695 U.S.A.
Dorothy J YouToxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695 U.S.A.
Ho Young LeeToxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695 U.S.A.
Alexia J Taylor-JustToxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695 U.S.A.
James C BonnerToxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695 U.S.A.
North Carolina State University · US

Funding

Toxicological Assessments for the Division of the National Toxicology ProgramZICES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2020 to 2021
$18.5M
TRAINING IN BIOCHEMICAL AND ENVIRONMENTAL TOXICOLOGYT32ES007046 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Seth William Kullman · 1985 to 2026
$5.1M
Genetic Susceptibility to Nanoparticle-Induced Respiratory DiseaseR01ES020897 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI BONNER, JAMES CHRISTOPHER · 2012 to 2017
$1.7M
NIEHS NIH HHS R01 ES020897NIEHS NIH HHS T32 ES007046
6 · The paper itself

Abstract

There is increasing evidence that inhaled multi-walled carbon nanotubes (MWCNTs) can have harmful effects on the respiratory system. Rodent studies suggest that individuals with asthma may be susceptible to the adverse pulmonary effects of MWCNTs. Asthma is an allergic lung disease characterized by a T

Indexed as

Nanotubes, CarbonPyroglyphidaeAnimalsLungMaleMiceMice, KnockoutSTAT6 Transcription FactorNanotubes, CarbonStat6 protein, mouseSTAT6 Transcription Factorallergensasthmacarbon nanotubeshouse dust miteSTAT6

Identifiers

PMID33860111
PMCPMC8043620
OpenAlexW3136920100

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.