Evidence map›Paper›PMID 33864109›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2022

Olfactory training with Aromastics: olfactory and cognitive effects.

Anna Oleszkiewicz, Laura Bottesi, Michal Pieniak, Shuji Fujita, Nadejda Krasteva, Gabriele Nelles, Thomas Hummel

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. The efficacy of olfactory training in improving olfactory function: a meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  2. Pooled it
  3. Retronasal Olfactory Function After Olfactory Training: A Prospective Single-Arm Study.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
    Article
  4. Article
  5. Assessment and behavioural management options for older adults with declined smell and taste functions: a scoping review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Olfactory Dysfunction and Cognitive Decline: Are They Related?Current allergy and asthma reports · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Four odorants for olfactory training are enough: a pilot study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Anna OleszkiewiczSmell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany. ania.oleszkiewicz@gmail.com.ORCID http://orcid.org/0000-0003-2217-1858
Laura BottesiSmell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Michal PieniakInstitute of Psychology, University of Wroclaw, ul. Dawida 1, 50-527, Wroclaw, Poland.
Shuji FujitaSony Corporation, New Business & Technology Development Group, 1-7-1 Konan Minato-ku, Tokyo, 108-0075, Japan.
Nadejda KrastevaSony Europe B.V., RD Center Stuttgart Laboratory 2, Hedelfingerstr. 61, 70327, Stuttgart, Germany.
Gabriele NellesSony Europe B.V., RD Center Stuttgart Laboratory 2, Hedelfingerstr. 61, 70327, Stuttgart, Germany.
Thomas HummelSmell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Technische Universität Dresden · DEUniversity of Wrocław · PLSony Computer Science Laboratories · JP

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego 626/STYP/12/2017Narodowe Centrum Nauki 2020/37/B/HS6/00288
6 · The paper itself

Abstract

purposeThe olfactory system can be successfully rehabilitated with regular, intermittent stimulation during multiple daily exposures to selected sets of odors, i.e., olfactory training (OT). OT has been repeatedly shown to be an effective tool of olfactory performance enhancement. Recent advancements in studies on OT suggest that its beneficial effects exceed olfaction and extend to specific cognitive tasks. So far, studies on OT provided compelling evidence for its effectiveness, but there is still a need to search for an optimal OT protocol. The present study examined whether increased frequency of OT leads to better outcomes in both olfactory and cognitive domains.

methodFifty-five subjects (28 females; M

resultsOT performed twice a day was more effective in supporting olfactory rehabilitation and interventions targeted to verbal semantic fluency than OT performed four times a day, even more so in subjects with lower baseline scores.

conclusionsOT is effective in supporting olfactory rehabilitation and interventions targeted to verbal semantic fluency. However, it may be prone to a ceiling effect, being efficient in subjects presenting with lower baseline olfactory performance and lower verbal semantic fluency.

Indexed as

Olfaction DisordersSmellAgedCognitionFemaleHumansMiddle AgedOdorantsOlfactionOlfaction disordersOlfactory rehabilitationOlfactory trainingSmell

Identifiers

PMID33864109
PMCPMC8051546
OpenAlexW3154342228

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.