ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2021
How does epigenetics influence the course of evolution?
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 174 citations in OpenAlex.
- The Role of Hydrogen Sulfide (HInternational journal of molecular sciences · 2023Pooled it
- Physiology can predict animal activity, exploration, and dispersal.Communications biology · 2022Pooled it
- Population epigenetics: deciphering DNA methylation diversity and its implications for health, disease, and evolution.Molecular biology and evolution · 2026Review
- Evolutionary Footprint: A Systemic Indicator in Evolution, Ecology and Conservation.Evolutionary applications · 2026Article
- Article
- A smartphone analogy to explore the origin of animals.The EMBO journal · 2026Review
- Epimutations: raw material for evolution?The EMBO journal · 2026Review
- New Method for Quantification of Phenotypic Plasticity Reveals How Plasticity Changes Over Time in the DiatomEcology and evolution · 2026Article
- Comparative Biologists and Aerospace Engineers: Important Allies to Explore the Secrets of Natural Flight.Integrative and comparative biology · 2026Article
- A Chromosome-Level Genome Assembly and Resequencing Data Reveal Low DNA Methylation and Reduced Diversity in the Solitary Bee Pollinator Osmia cornuta.Genome biology and evolution · 2026Article
- Transgenerational reproductive risks of BPA: epigenetic mechanisms and biomarker applications. A critical review.Environmental epigenetics · 2026Review
- Reframing neuroergonomics in an evolutionary and active inference context.Frontiers in neuroergonomics · 2026Article
- Article
- Reversibility of sex changes in the plant kingdom: more important than we thought?Biological reviews of the Cambridge Philosophical Society · 2025Review
- Systematic enhancer mapping and functional analysis in zebrafish with optimized CRISPR interference.Nucleic acids research · 2025Article
- Towards a Research Programme Aiming at Causes and Consequences of Reticulate Evolution.Biology · 2025Review
- Convergent Evolution and the Epigenome.Epigenomes · 2025Review
- Environmental Toxicants in the Hispanic Community Epigenetically Contributing to Preeclampsia.Cardiovascular toxicology · 2025Review
- Applying Genomic Offsets to Breeding Programmes: Bridging Evolutionary Insights With Practical Applications.Evolutionary applications · 2025Article
- Evolutionary Consequences of Unusually Large Pericentric TE-rich Regions in the Genome of a Neotropical Fig Wasp.Genome biology and evolution · 2025Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epigenetics is the study of changes in gene activity that can be transmitted through cell divisions but cannot be explained by changes in the DNA sequence. Epigenetic mechanisms are central to gene regulation, phenotypic plasticity, development and the preservation of genome integrity. Epigenetic mechanisms are often held to make a minor contribution to evolutionary change because epigenetic states are typically erased and reset at every generation, and are therefore, not heritable. Nonetheless, there is growing appreciation that epigenetic variation makes direct and indirect contributions to evolutionary processes. First, some epigenetic states are transmitted intergenerationally and affect the phenotype of offspring. Moreover,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.