Evidence map›Paper›PMID 33868225›Full record

ArticleFrontiers in immunology2021

Single-Nucleotide Variants in the AIM2 - Absent in Melanoma 2 Gene (rs1103577) Associated With Protection for Tuberculosis.

Mariana Brasil de Andrade Figueira, Dhêmerson Souza de Lima, Antonio Luiz Boechat, Milton Gomes do Nascimento Filho, Irineide Assumpção Antunes, Joycenéa da Silva Matsuda, Thaís Rodrigues de Albuquerque Ribeiro, Luana Sousa Felix, Ariane Senna Fonseca Gonçalves, Allyson Guimarães da Costa and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Can We Exploit Inflammasomes for Host-Directed Therapy in the Fight againstInternational journal of molecular sciences · 2024
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  4. Article
  5. Article
  6. Review
  7. Pyroptosis-related genesFrontiers in genetics · 2023
    Article
  8. Article
  9. Research progress on genetic control of host susceptibility to tuberculosis.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Mariana Brasil de Andrade FigueiraLaboratório de Imunologia Molecular, Departamento de Parasitologia, Universidade Federal do Amazonas (UFAM), Manaus, Brazil.
Dhêmerson Souza de LimaLaboratório de Imunogenética, Departamento de Imunologia, Instituto de Ciências Biomédicas (ICB), Universidade de São Paulo (USP), São Paulo, Brazil.
Antonio Luiz BoechatLaboratório de Imunologia Molecular, Departamento de Parasitologia, Universidade Federal do Amazonas (UFAM), Manaus, Brazil.
Milton Gomes do Nascimento FilhoLaboratório de Imunologia Molecular, Departamento de Parasitologia, Universidade Federal do Amazonas (UFAM), Manaus, Brazil.
Irineide Assumpção AntunesPoliclínica Cardoso Fontes - Secretaria de Estado da Saúde do Amazonas-SUSAM, Manaus, Brazil.
Joycenéa da Silva MatsudaPoliclínica Cardoso Fontes - Secretaria de Estado da Saúde do Amazonas-SUSAM, Manaus, Brazil.
Thaís Rodrigues de Albuquerque RibeiroLaboratório de Imunologia Molecular, Departamento de Parasitologia, Universidade Federal do Amazonas (UFAM), Manaus, Brazil.
Luana Sousa FelixLaboratório de Imunologia Molecular, Departamento de Parasitologia, Universidade Federal do Amazonas (UFAM), Manaus, Brazil.
Ariane Senna Fonseca GonçalvesLaboratório de Imunologia Molecular, Departamento de Parasitologia, Universidade Federal do Amazonas (UFAM), Manaus, Brazil.
Allyson Guimarães da CostaPrograma de Pós-Graduação em Imunologia Básica e Aplicada, Universidade Federal do Amazonas, Manaus, Brazil.
Rajendranath RamasawmyPrograma de Pós-Graduação em Imunologia Básica e Aplicada, Universidade Federal do Amazonas, Manaus, Brazil.
Alessandra PontilloLaboratório de Imunogenética, Departamento de Imunologia, Instituto de Ciências Biomédicas (ICB), Universidade de São Paulo (USP), São Paulo, Brazil.
Mauricio Morishi OguskuLaboratório de Micobacteriologia, Instituto Nacional de Pesquisas da Amazônia (INPA), Manaus, Brazil.
Aya SadahiroLaboratório de Imunologia Molecular, Departamento de Parasitologia, Universidade Federal do Amazonas (UFAM), Manaus, Brazil.
Universidade Federal do Amazonas · BRUniversidade de São Paulo · BRNational Institute of Amazonian Research · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) remains a serious public health burden worldwide. TB is an infectious disease caused by the

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAllelesBrazilCARD Signaling Adaptor ProteinsCase-Control StudiesCytokinesDisease ResistanceDNA-Binding ProteinsFemaleGenotypeHumansMaleMycobacterium tuberculosisOdds RatioTuberculosisAIM2 protein, humanCARD Signaling Adaptor ProteinsCytokinesDNA-Binding ProteinsAIM2CARD8CTSBinflammasomeSNVtuberculosis

Identifiers

PMID33868225
PMCPMC8047195
OpenAlexW3151308909

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.