Evidence mapPaperPMID 33870263Full record

ArticleEndocrines2021

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus.

Konstantina Dipla, Andreas Zafeiridis, Gesthimani Mintziori, Afroditi K Boutou, Dimitrios G Goulis, Anthony C Hackney

Open access · goldAbstract read
In one paragraph

Article in Endocrines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. The Association of Nutrition and Exercise Behaviors of Women with Diabetes in Pregnancy with Infant Breastfeeding Practices.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2023
    Article
  10. Review
  11. Article
  12. Gut Microbiome Changes in Gestational Diabetes.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Konstantina DiplaLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, 621 22 Serres, Greece.ORCID 0000-0001-5902-3467
Andreas ZafeiridisLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, 621 22 Serres, Greece.
Gesthimani MintzioriUnit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, School of Medicine, Aristotle University of Thessaloniki, "Papageorgiou" General Hospital, 56429 Thessaloniki, Greece.
Afroditi K BoutouDepartment of Respiratory Medicine, "G. Papanikolaou" General Hospital, 57010 Exohi, Thessaloniki, Greece.ORCID 0000-0001-7366-2038
Dimitrios G GoulisUnit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, School of Medicine, Aristotle University of Thessaloniki, "Papageorgiou" General Hospital, 56429 Thessaloniki, Greece.
Anthony C HackneyDepartment of Exercise & Sport Science, Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina, NC 27599-8700, USA.
Aristotle University of Thessaloniki · GRG. Papanikolaou General Hospital · GRUniversity of North Carolina at Chapel Hill · US

Funding

NIAMS NIH HHS R03 AR055262
6 · The paper itself

Abstract

Gestational Diabetes Mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. Regular exercise is important for a healthy pregnancy and can lower the risk of developing GDM. For women with GDM, exercise is safe and can affect the pregnancy outcomes beneficially. A single exercise bout increases skeletal muscle glucose uptake, minimizing hyperglycemia. Regular exercise training promotes mitochondrial biogenesis, improves oxidative capacity, enhances insulin sensitivity and vascular function, and reduces systemic inflammation. Exercise may also aid in lowering the insulin dose in insulin-treated pregnant women. Despite these benefits, women with GDM are usually inactive or have poor participation in exercise training. Attractive individualized exercise programs that will increase adherence and result in optimal maternal and offspring benefits are needed. However, as women with GDM have a unique physiology, more attention is required during exercise prescription. This review (i) summarizes the cardiovascular and metabolic adaptations due to pregnancy and outlines the mechanisms through which exercise can improve glycemic control and overall health in insulin resistance states, (ii) presents the pathophysiological alterations induced by GDM that affect exercise responses, and (iii) highlights cardinal points of an exercise program for women with GDM.

Indexed as

diabetesexerciseexercise endocrinologyexercise physiologyhormonespregnancypregnancy endocrinologywomen’s health

Identifiers

PMID33870263
PMCPMC8046020
OpenAlexW3139343330

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.