Evidence mapPaperPMID 33870722Full record

Trial reportPhysiological genomics2021

Muscle transcriptional networks linked to resistance exercise training hypertrophic response heterogeneity.

Kaleen M Lavin, Margaret B Bell, Jeremy S McAdam, Bailey D Peck, R Grace Walton, Samuel T Windham, S Craig Tuggle, Douglas E Long, Philip A Kern, Charlotte A Peterson and 1 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiological genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
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  3. Review
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  8. Article
  9. Review
  10. Article
  11. Article
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  15. Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2022
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Kaleen M LavinCenter for Exercise Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-1426-8174
Margaret B BellCenter for Exercise Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Jeremy S McAdamCenter for Exercise Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Bailey D PeckDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky.
R Grace WaltonDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky.
Samuel T WindhamCenter for Exercise Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
S Craig TuggleCenter for Exercise Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Douglas E LongDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky.
Philip A KernDivision of Endocrinology, Department of Internal Medicine, and Barnstable Brown Diabetes and Obesity Center, University of Kentucky, Lexington, Kentucky.
Charlotte A PetersonDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky.
Marcas M BammanCenter for Exercise Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-5017-5453
University of Kentucky · USUniversity of Alabama at Birmingham · USFlorida Institute for Human and Machine Cognition · US

Funding

The Exercise and Physical Activity Collaborative Team (ExPACT): a Proposed MoTrPAC Clinical CenterU01AR071133 · NIAMS · BALL STATE UNIVERSITY · PI Thomas W Buford, Bret H Goodpaster · 2022 to 2022
$7.3M
Interdisciplinary Training in Pathobiology and Rehabilitation Medicine.T32HD071866 · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2025 to 2025
$505k
NIAMS NIH HHS U01 AR071133NIA NIH HHS F32 AG062048NIA NIH HHS F32AG062048NIA NIH HHS R01 AG046920NIA NIH HHS R01AG046920NICHD NIH HHS P2C HD086851NICHD NIH HHS T32 HD071866NICHD NIH HHS T32HD071866
6 · The paper itself

Abstract

The skeletal muscle hypertrophic response to resistance exercise training (RT) is highly variable across individuals. The molecular underpinnings of this heterogeneity are unclear. This study investigated transcriptional networks linked to RT-induced muscle hypertrophy, classified as

Indexed as

Gene Regulatory NetworksResistance TrainingAbsorptiometry, PhotonAgedFemaleHumansMaleMuscle, SkeletalSkeletal Muscle Enlargementmuscle growthnetwork biologyresistance exerciseRNA-seqskeletal muscle

Identifiers

PMID33870722
PMCPMC8424535
OpenAlexW3154863794

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.