Evidence map›Paper›PMID 33870723›Full record

ArticlePhysiological genomics2021

Whole genome transcriptome analysis of the stomach resected in human vertical sleeve gastrectomy: cutting more than calories.

William C Dungan, Michael R Garrett, Bradley A Welch, William J Lawson, Alexandra R Himel, Adam Dungey, Kenneth D Vick, Bernadette E Grayson

Open access · greenAbstract read
In one paragraph

Article in Physiological genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. A Novel Role for Coilin in Vertebrate Innate Immunity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

William C DunganDepartment of Neurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson, Mississippi.
Michael R GarrettDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0001-5234-7928
Bradley A WelchDepartment of Neurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson, Mississippi.
William J LawsonDepartment of Neurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson, Mississippi.
Alexandra R HimelDepartment of Neurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson, Mississippi.
Adam DungeyDepartment of Surgery, University of Mississippi Medical Center, Jackson, Mississippi.
Kenneth D VickDepartment of Surgery, University of Mississippi Medical Center, Jackson, Mississippi.
Bernadette E GraysonDepartment of Neurobiology and Anatomical Sciences, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0002-1281-1682
University of Mississippi Medical Center · USJackson Memorial Hospital · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Pier Paolo Claudio, Babbette LaMarca · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, JOHN E · 2013 to 2022
$23.4M
NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P20GM103476NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20GM104357NIGMS NIH HHS P20 GM121334NIGMS NIH HHS P20GM121334
6 · The paper itself

Abstract

Vertical sleeve gastrectomy (VSG) is a surgical weight loss procedure that resects 80% of the stomach, creating a tube linking the esophagus to the duodenum. Because of the efficacy and relative simplicity of VSG, it is preferred in the United States, with VSG currently at >61% of bariatric surgeries performed. Surprisingly, there has never been a complete molecular characterization of the human stomach greater curvature's fundus and corpus. Here we compare and contrast the molecular makeup of these regions. We performed a prospective cohort study to obtain gastric tissue samples from patients undergoing elective VSG. Paired fundus and corpus samples were obtained. Whole genome transcriptome analysis was performed by RNA sequencing (

Indexed as

AdultBariatric SurgeryFemaleGastrectomyGene Expression ProfilingGenome, HumanHumansMaleMiddle AgedStomachTranscriptomeYoung Adultbariatric surgerydiabetesfundusgreater curvatureobesitystomach

Identifiers

PMID33870723
PMCPMC8424537
OpenAlexW3154311098

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.