Evidence map›Paper›PMID 33871821›Full record

ReviewNeuroscience bulletin2021

Neuromodulation-Based Stem Cell Therapy in Brain Repair: Recent Advances and Future Perspectives.

Ti-Fei Yuan, Yi Dong, Li Zhang, Jieyu Qi, Chun Yao, Yongjun Wang, Renjie Chai, Yan Liu, Kwok-Fai So

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
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  4. Review
  5. Targeting the insular cortex for neuropathic pain modulation: Insights into synaptic and neuronal mechanisms.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Syndromic Deafness GeneFrontiers in cell and developmental biology · 2021
    Article
  15. Frontiers in cell and developmental biology · 2021
    Article
  16. Cochlear Sox2Frontiers in cell and developmental biology · 2021
    Article
  17. Promising Applications of Nanoparticles in the Treatment of Hearing Loss.Frontiers in cell and developmental biology · 2021
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Ti-Fei Yuan *Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.ORCID https://orcid.org/0000-0003-0510-715X
Yi Dong *Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education, East China Normal University, Shanghai, 200241, China.
Li Zhang *Joint International Research Laboratory of CNS Regeneration, Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China.
Jieyu QiKey Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing, 210096, China.
Chun YaoCo-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China.
Yongjun WangCo-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China. wyjbs@ntu.edu.cn.
Renjie ChaiCo-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China. renjiec@seu.edu.cn.
Yan LiuCo-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China. yanliu@njmu.edu.cn.
Kwok-Fai SoState Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Jiulong, Hong Kong SAR, China. hrmaskf@hku.hk.
Nantong University · CNEast China Normal University · CNHong Kong Baptist University · HKJinan University · CNShanghai Jiao Tong University · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell transplantation holds a promising future for central nervous system repair. Current challenges, however, include spatially and temporally defined cell differentiation and maturation, plus the integration of transplanted neural cells into host circuits. Here we discuss the potential advantages of neuromodulation-based stem cell therapy, which can improve the viability and proliferation of stem cells, guide migration to the repair site, orchestrate the differentiation process, and promote the integration of neural circuitry for functional rehabilitation. All these advantages of neuromodulation make it one potentially valuable tool for further improving the efficiency of stem cell transplantation.

Indexed as

Deep Brain StimulationTranscranial Magnetic StimulationBrainHumansNeuronsStem Cell TransplantationDeep brain stimulationNeuromodulationRehabilitationStem cellTranscranial direct current stimulationTranscranial magnetic stimulation

Identifiers

PMID33871821
PMCPMC8099989
OpenAlexW3152712269

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.