Evidence map›Paper›PMID 33879025›Full record

ArticleAutophagy2021

Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P

Matthew J Eramo, Rajendra Gurung, Christina A Mitchell, Meagan J McGrath

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Review
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  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew J EramoCancer Program, and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Australia.ORCID 0000-0002-5894-1589
Rajendra GurungCancer Program, and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Australia.
Christina A MitchellCancer Program, and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Australia.ORCID 0000-0001-9372-3192
Meagan J McGrathCancer Program, and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Australia.ORCID 0000-0002-9414-6558
Australian Regenerative Medicine Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagic lysosome reformation (ALR) recycles autolysosome membranes formed during autophagy, to make lysosomes and is essential for continued autophagy function. Localized membrane remodeling on autolysosomes leads to the extension of reformation tubules, which undergo scission to form new lysosomes. The phosphoinositides phosphatidylinositol-4-phosphate (PtdIns4P) and phosphatidylinositol-4,5-bisphosphate (PtdIns[4,5]P

Indexed as

AutophagyPhosphatidylinositolsAnimalsLysosomesMiceMuscle, SkeletalPhosphatidylinositol Phosphatesphosphatidylinositol 4-phosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsAutophagic lysosome reformationautophagyinositol polyphosphate 5-phosphataseINPP5Klysosomemuscular dystrophyphosphoinositidePtdIns(4, 5)P2PtdIns4Pskeletal muscle

Identifiers

PMID33879025
PMCPMC8143231
OpenAlexW3156639785

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.