Evidence map›Paper›PMID 33880425›Full record

ArticleTranslational medicine of aging2020

Advances in quantitative biology methods for studying replicative aging in

Richard O'Laughlin, Meng Jin, Yang Li, Lorraine Pillus, Lev S Tsimring, Jeff Hasty, Nan Hao

Abstract read
In one paragraph

Article in Translational medicine of aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
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  14. Review
  15. Review
  16. Replicative Aging in Pathogenic Fungi.Journal of fungi (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Richard O'LaughlinDepartment of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Meng JinBioCircuits Institute, University of California San Diego, La Jolla, CA, 92093, USA.
Yang LiSection of Molecular Biology, Division of Biological Sciences, University of California San Diego, La Jolla, CA, 92093, USA.
Lorraine PillusSection of Molecular Biology, Division of Biological Sciences, University of California San Diego, La Jolla, CA, 92093, USA.
Lev S TsimringBioCircuits Institute, University of California San Diego, La Jolla, CA, 92093, USA.
Jeff HastyDepartment of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Nan HaoBioCircuits Institute, University of California San Diego, La Jolla, CA, 92093, USA.

Funding

Network-Driven Dynamics of Replicative AgingR01AG056440 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEFF M HASTY, Nan Hao · 2017 to 2026
$5.6M
NIA NIH HHS R01 AG056440
6 · The paper itself

Abstract

Aging is a complex, yet pervasive phenomenon in biology. As human cells steadily succumb to the deteriorating effects of aging, so too comes a host of age-related ailments such as neurodegenerative disorders, cardiovascular disease and cancer. Therefore, elucidation of the molecular networks that drive aging is of paramount importance to human health. Progress toward this goal has been aided by studies from simple model organisms such as

Identifiers

PMID33880425
PMCPMC8054985

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.