ReviewLangenbeck's archives of surgery2021
Management of primary and renal hyperparathyroidism: guidelines from the German Association of Endocrine Surgeons (CAEK).
Review in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Timing of parathyroidectomy in kidney transplant candidates: a systematic review and a proposed clinical algorithm.Frontiers in endocrinology · 2026Pooled it
- Comparing 24 h Urine and Spot Urine Calcium Measurements in Clinical Routine: Accuracy and Limitations.Journal of clinical medicine · 2026Article
- Hyperparathyroidism: historical milestones and modern therapeutic strategies.Wiener klinische Wochenschrift · 2026Review
- Primary hyperparathyroidism: targeted, focused exploration with "selective" parathyroidectomy : Minimally invasive open vs. minimally invasive video-assisted vs. endoscopic approach.Wiener klinische Wochenschrift · 2026Review
- Neuropsychiatric manifestations of primary hyperparathyroidism.Wiener klinische Wochenschrift · 2026Review
- Primary Hyperparathyroidism in the Pediatric Population: Surgical Considerations and Outcomes: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Parathyroid autotransplantation: a phase-based framework for surgical decision-making.Frontiers in endocrinology · 2026Review
- Diagnostic performance of 3T MRI preoperative localization of parathyroid adenomas in primary hyperparathyroidism.Frontiers in endocrinology · 2026Article
- Hyperparathyroidism: current concepts in diagnosis and surgical treatment.Frontiers in endocrinology · 2026Review
- Short-term biochemical outcomes after microwave ablation versus parathyroidectomy for primary hyperparathyroidism: an IPTW analysis.Frontiers in endocrinology · 2026Article
- Synchronous Primary Hyperparathyroidism and Polycythemia Vera: A Case Report and Literature Review.Clinical case reports · 2025Article
- [Parathyroid glands and their anatomical positional variations : Preoperative diagnostics and surgical planning].Chirurgie (Heidelberg, Germany) · 2025Review
- Do stricter criteria for intraoperative parathyroid hormone monitoring reduce the risk of persistence or reoperation in primary hyperparathyroidism? A receiver operating characteristic analysis.Langenbeck's archives of surgery · 2025Article
- Article
- Primary Hyperparathyroidism: An Analysis Amid the Co-Occurrence of Type 2 Diabetes Mellitus.Life (Basel, Switzerland) · 2025Review
- [Ultrafast intraoperative monitoring of parathyroid hormone-Results of a prospective multicenter validation study].Chirurgie (Heidelberg, Germany) · 2025Article
- [Multimorbid patients in endocrine surgery].Chirurgie (Heidelberg, Germany) · 2025Article
- Diagnostic Ability and Correlation of DigitalNuclear medicine and molecular imaging · 2025Article
- Article
- Bone Mineral Density and First Line Imaging with [Diagnostics (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
32 authors at 20 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe purpose of this review is to provide updated recommendations for the surgical management of primary (pHPT) and renal (rHPT) hyperparathyroidism, formulating a new guideline of the German Association of Endocrine Surgeons (CAEK).
methodsEvidence-based recommendations for the diagnosis and therapy of pHPT and rHPT were assessed by a multidisciplinary panel using PubMed for a comprehensive literature search together with a structured consensus dialogue (S2k guideline of the Association of the German Scientific Medical Societies, AWMF).
resultsDuring the last 20 years, a variety of new preoperative localization procedures, such as sestamibi-SPECT, 4D-CT, and various PET/CT procedures, were established for pHPT. High-resolution imaging, together with intraoperative parathyroid hormone (IOPTH) measurement, enabled focused or minimally invasive surgery to become the most favored surgical technique. Patients with pHPT and nonlocalizing imaging have a higher risk of multiglandular disease. Surgical therapy provides very high cure rates, with a clear relation to the surgeon's experience in parathyroid procedures. Reoperative parathyroidectomy, children with pHPT or familial forms, and parathyroid carcinoma are addressed and require special surgical expertise. A multidisciplinary team of experienced nephrologists, transplant, and endocrine surgeons should assess the diagnosis and treatment of renal HPT.
conclusionSurgery is the only curative treatment for pHPT and should be considered for all patients with pHPT. For rHPT, a more selective approach is required, and parathyroidectomy is indicated only when conservative treatment options fail. In parathyroid carcinoma, the adequacy of local resection influences local disease control.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.