Evidence map›Paper›PMID 33882807›Full record

SynthesisCurrent neuropharmacology2021

Essential Oils in Experimental Models of Neuropsychiatric Disorders: A Systematic Review.

Luciana Cristina B Fernandes, Ianara Mendonça Costa, Marco Aurelio M Freire, Francisca Overlânia V Lima, Francisca Idalina Neta, Eudes Euler de Souza Lucena, Rodrigo Dias Alves, Jose Rodolfo Lopes P Cavalcanti, Francisco Irochima Pinheiro, Eduardo Pereira de Azevedo and 2 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Current neuropharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Inhalation AromatherapyFrontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Luciana Cristina B FernandesGraduate Program of Animal Science, Federal Rural University of the Semi Arid (UFERSA), Mossoro/RN, Brazil.
Ianara Mendonça CostaLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Marco Aurelio M FreireLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Francisca Overlânia V LimaLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Francisca Idalina NetaLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Eudes Euler de Souza LucenaLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Rodrigo Dias AlvesLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Jose Rodolfo Lopes P CavalcantiLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Francisco Irochima PinheiroPostgraduate Program of Biotechnology, Health School, Laureate International Universities - Potiguar University (UnP), Natal/RN, Brazil.
Eduardo Pereira de AzevedoPostgraduate Program of Biotechnology, Health School, Laureate International Universities - Potiguar University (UnP), Natal/RN, Brazil.
Carlos Iberê A FreitasGraduate Program of Animal Science, Federal Rural University of the Semi Arid (UFERSA), Mossoro/RN, Brazil.
Fausto Pierdoná GuzenLaboratory of Experimental Neurology, Department of Biomedical Sciences, Faculty of Health Sciences, University of the State of Rio Grande do Norte (UERN), Mossoro/RN, Brazil.
Universidade do Estado do Rio Grande do Norte · BRUniversidade Federal Rural do Semi-Árido · BRUniversidade Potiguar · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeural cells undergo functional or sensory loss due to neurological disorders. In addition to environmental or genetic factors, oxidative stress is a major contributor to neurodegeneration. In this context, there has been a growing interest in investigating the effects of EOs (EOs) in recent years, especially in the treatment of neuropathologies. The chemical and biological effects of EOs have led to important treatment tools for the management of various neurological disorders.

objectiveIn the present study we performed a systematic review that sought to comprehend the neuroprotective effects of different EOs.

methodThis work is a systematic review where an electronic search was performed on PubMed, ScienceDirect, Cochrane Library and SciELO (Scientific Electronic Library Online) databases, covering the last 10 years, using "Essential oil" and "Neuroprotective effect" as reference terms.

resultsA total of 9 articles were identified, in which the efficacy of EOs was described in experimental models of anxiety, dementia, oxidative stress, cerebral ischemia, Alzheimer's disease, and oxidative toxicity.

conclusionEOs from different species of medicinal plants have shown positive responses in neurological disorders such as anxiety, dementia, oxidative stress, cerebral ischemia, and oxidative toxicity. Thus, EOs emerges with the potential to be used as alternative agents in the treatment of neurological disorders.

Indexed as

Alzheimer DiseaseNeuroprotective AgentsOils, VolatileHumansModels, TheoreticalOxidative StressNeuroprotective AgentsOils, Volatileantioxidantbrain.essential oilsNeurodegenerative diseasesneuroprotectionoxidative stress

Identifiers

PMID33882807
PMCPMC8977636
OpenAlexW3153706042

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.