Evidence map›Paper›PMID 33889127›Full record

SynthesisFrontiers in neurology2021

Gene Therapy in Movement Disorders: A Systematic Review of Ongoing and Completed Clinical Trials.

Aristide Merola, Noelle Kobayashi, Alberto Romagnolo, Brenton A Wright, Carlo Alberto Artusi, Gabriele Imbalzano, Irene Litvan, Amber D Van Laar, Krystof Bankiewicz

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Genetic Testing of Movements Disorders: A Review of Clinical Utility.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024
    Review
  3. Review
  4. Neurosurgical management of non-spastic movement disorders.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
  5. Functional Brain Networks to Evaluate Treatment Responses in Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  6. Article
  7. Review
  8. Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Aristide MerolaDepartment of Neurology, Madden Center for Parkinson Disease and Other Movement Disorders, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Noelle KobayashiThe Ohio State University, Columbus, OH, United States.
Alberto RomagnoloDepartment of Neuroscience "Rita Levi Montalcini," University of Turin, Turin, Italy.
Brenton A WrightDepartment of Neurosciences, Parkinson and Other Movement Disorders Center, University of California, San Diego, La Jolla, CA, United States.
Carlo Alberto ArtusiDepartment of Neuroscience "Rita Levi Montalcini," University of Turin, Turin, Italy.
Gabriele ImbalzanoDepartment of Neuroscience "Rita Levi Montalcini," University of Turin, Turin, Italy.
Irene LitvanDepartment of Neurosciences, Parkinson and Other Movement Disorders Center, University of California, San Diego, La Jolla, CA, United States.
Amber D Van LaarAsklepios BioPharmaceutical Inc., Research Triangle, NC, United States.
Krystof BankiewiczDepartment of Neurological Surgery, College of Medicine, The Ohio State University, Columbus, OH, United States.
University of Turin · ITUniversity of California, San Diego · USNeurological Surgery · USThe Ohio State University · USThe Ohio State University Wexner Medical Center · USUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amino acid decarboxylase deficiencyataxiagene therapyHuntingtonmovement disordermultiple system atrophyParkinson

Identifiers

PMID33889127
PMCPMC8056023
OpenAlexW3146338927

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.