Evidence mapPaperPMID 33890822Full record

ArticleCirculation research2021

Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury.

Nirupama Ramkumar, Deborah Stuart, Caitlin S Peterson, Chunyan Hu, William Wheatley, Jae Min Cho, J David Symons, Donald E Kohan

Open access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
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  9. Article
  10. Functional Roles of Furin in Cardio-Cerebrovascular Diseases.ACS pharmacology & translational science · 2024
    Review
  11. Article
  12. The (pro)renin receptor as a pharmacological target in cardiorenal diseaes.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nirupama RamkumarDivision of Nephrology and Hypertension (N.R., D.S., C.S.P., C.H., W.W., D.E.K.), University of Utah Health, Salt Lake City.
Deborah StuartDivision of Nephrology and Hypertension (N.R., D.S., C.S.P., C.H., W.W., D.E.K.), University of Utah Health, Salt Lake City.
Caitlin S PetersonDivision of Nephrology and Hypertension (N.R., D.S., C.S.P., C.H., W.W., D.E.K.), University of Utah Health, Salt Lake City.
Chunyan HuDivision of Nephrology and Hypertension (N.R., D.S., C.S.P., C.H., W.W., D.E.K.), University of Utah Health, Salt Lake City.
William WheatleyDivision of Nephrology and Hypertension (N.R., D.S., C.S.P., C.H., W.W., D.E.K.), University of Utah Health, Salt Lake City.
Jae Min ChoNutrition and Integrative Physiology (J.M.C., J.D.S.), University of Utah Health, Salt Lake City.
J David SymonsNutrition and Integrative Physiology (J.M.C., J.D.S.), University of Utah Health, Salt Lake City.
Donald E KohanDivision of Nephrology and Hypertension (N.R., D.S., C.S.P., C.H., W.W., D.E.K.), University of Utah Health, Salt Lake City.
University of Utah · US

Funding

NHLBI NIH HHS P01 HL136267NHLBI NIH HHS R01 HL141540NIDDK NIH HHS P30 DK079307
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Angiotensin IIBlood PressureAnimalsDisease Models, AnimalHypertensionKidneyKidney DiseasesMaleMesenteric ArteriesMiceMice, Inbred C57BLMice, Mutant StrainsMutationProrenin ReceptorProton-Translocating ATPasesReceptors, Cell SurfaceAngiotensin IIATP6AP2 protein, mouseProrenin ReceptorProton-Translocating ATPasesReceptors, Cell Surfaceblood pressurehypertensionkidneyplasmarenin-angiotensin system

Identifiers

PMID33890822
PMCPMC8225587
OpenAlexW3154456345

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.