Evidence map›Paper›PMID 33891015›Full record

ReviewEndocrinology2021

Cardiovascular Neuroendocrinology: Emerging Role for Neurohypophyseal Hormones in Pathophysiology.

Ato O Aikins, Dianna H Nguyen, Obed Paundralingga, George E Farmer, Caroline Gusson Shimoura, Courtney Brock, J Thomas Cunningham

Abstract readReview
In one paragraph

Review in Endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Interplay between volemic balance and the intestinal tract: insights on biomarkers and diagnostic tests used to assess intestinal morphofunctional barrier.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Review
  3. Review
  4. Discovery and evaluation of a novelActa pharmaceutica Sinica. B · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Norepinephrine innervation of the supraoptic nucleus contributes to increased copeptin and dilutional hyponatremia in male rats.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  10. The expanding role of peptides in cardiovascular care.Diabetes & vascular disease research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ato O AikinsDepartment of Physiology and Anatomy, Graduate School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX 76107, USA.ORCID 0000-0001-8936-1053
Dianna H NguyenDepartment of Physiology and Anatomy, Graduate School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX 76107, USA.
Obed PaundralinggaDepartment of Physiology and Anatomy, Graduate School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX 76107, USA.
George E FarmerDepartment of Physiology and Anatomy, Graduate School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX 76107, USA.ORCID 0000-0002-6099-0080
Caroline Gusson ShimouraDepartment of Physiology and Anatomy, Graduate School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX 76107, USA.ORCID 0000-0002-6255-0572
Courtney BrockDepartment of Physiology and Anatomy, Graduate School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX 76107, USA.
J Thomas CunninghamDepartment of Physiology and Anatomy, Graduate School of Biomedical Sciences, UNT Health Science Center, Fort Worth, TX 76107, USA.ORCID 0000-0001-8859-9481

Funding

Training in the Neurobiology of Aging and Alzheimer's DiseaseT32AG020494 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI ROBERT Clinton BARBER, NATHALIE SUMIEN · 2002 to 2026
$6.9M
Neural Regulation of Vasopressin Release in a Model of Dilutional HyponatremiaR01HL142341 · NHLBI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI CUNNINGHAM, J THOMAS · 2018 to 2021
$2.2M
NHLBI NIH HHS R01 HL142341NIA NIH HHS T32 AG020494
6 · The paper itself

Abstract

Arginine vasopressin (AVP) and oxytocin (OXY) are released by magnocellular neurosecretory cells that project to the posterior pituitary. While AVP and OXY currently receive more attention for their contributions to affiliative behavior, this mini-review discusses their roles in cardiovascular function broadly defined to include indirect effects that influence cardiovascular function. The traditional view is that neither AVP nor OXY contributes to basal cardiovascular function, although some recent studies suggest that this position might be re-evaluated. More evidence indicates that adaptations and neuroplasticity of AVP and OXY neurons contribute to cardiovascular pathophysiology.

Indexed as

Blood PressureAnimalsArginine VasopressinBlood VolumeCardiovascular DiseasesCardiovascular SystemHumansHypothalamo-Hypophyseal SystemNatriuresisOxytocinReceptors, OxytocinReceptors, VasopressinSex CharacteristicsArginine VasopressinOxytocinReceptors, OxytocinReceptors, Vasopressinheart failurehypertensionoxytocinvasopressin

Identifiers

PMID33891015
PMCPMC8234498

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.