Evidence mapPaperPMID 33901010Full record

Observational studyAging2021

Long noncoding RNA DLGAP1-AS1 promotes the progression of glioma by regulating the miR-1297/EZH2 axis.

Liang Liu, Xiaojian Li, Yan Shi, Hua Chen

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Advanced biomedical research · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Liang LiuDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Xiaojian LiDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Yan ShiDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Hua ChenDepartment of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysregulated lncRNAs have been implicated in a plethora of tumors, including glioma. One such oncogenic lncRNAs that has been reported in several cancers is the lncRNA DLGAP1 antisense RNA 1 (DLGAP1-AS1). This study seeks to characterize the expression of DLGAP1-AS1 in glioma tissues, which we found to be raised in both glioma samples and cell lines. Functional experiments revealed that DLGAP1-AS1 promoted

Indexed as

AnimalsBrainBrain NeoplasmsCell Line, TumorCell MovementCell ProliferationCraniotomyDatasets as TopicDisease ProgressionEnhancer of Zeste Homolog 2 ProteinGene Expression Regulation, NeoplasticGene Knockdown TechniquesGliomaHumansMaleMiceEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanMicroRNAsMIRN1297 microRNA, humanRNA, Long NoncodingDLGAP1-AS1EZH2gliomamiR-1297

Identifiers

PMID33901010
PMCPMC8109124
OpenAlexW3157931678

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.