Evidence map›Paper›PMID 33907541›Full record

ArticleEXCLI journal2021

Up-regulation of miR-155 potentiates CD34+ CML stem/progenitor cells to escape from the growth-inhibitory effects of TGF-ß1 and BMP signaling.

Touba Mahdloo, Pantea Sahami, Reihaneh Ramezani, Mojtaba Jafarinia, Hamedreza Goudarzi, Sadegh Babashah

Open access · greenAbstract read
In one paragraph

Article in EXCLI journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Touba MahdlooDepartment of Genetics, Faculty of Basic Sciences, Islamic Azad University, Marvdasht, Iran.
Pantea SahamiDepartment of Biomedical Sciences, Women Research Center, University of Alzahra, Tehran, Iran.
Reihaneh RamezaniDepartment of Biomedical Sciences, Women Research Center, University of Alzahra, Tehran, Iran.
Mojtaba JafariniaDepartment of Genetics, Faculty of Basic Sciences, Islamic Azad University, Marvdasht, Iran.
Hamedreza GoudarziDepartment of Genetics, Faculty of Basic Sciences, Islamic Azad University, Marvdasht, Iran.
Sadegh BabashahDepartment of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0000-0001-7066-0918
Tarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

microRNAs (miRNAs or miRs) play key roles in different stages of chronic myeloid leukemia (CML) pathogenesis. The present study aimed to demonstrate whether miR-155 enables CD34

Indexed as

bone morphogenetic proteinchronic myeloid leukemiamiR-155TGF-beta signaling

Identifiers

PMID33907541
PMCPMC8073837
OpenAlexW3157566088

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.