Evidence map›Paper›PMID 33909459›Full record

ReviewAnnual review of genomics and human genetics2021

Threespine Stickleback: A Model System For Evolutionary Genomics.

Kerry Reid, Michael A Bell, Krishna R Veeramah

Abstract readReview
In one paragraph

Review in Annual review of genomics and human genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kerry ReidDepartment of Ecology and Evolution, Stony Brook University, Stony Brook, New York 11794, USA; email: krishna.veeramah@stonybrook.edu.
Michael A BellUniversity of California Museum of Paleontology, Berkeley, California 94720, USA.
Krishna R VeeramahDepartment of Ecology and Evolution, Stony Brook University, Stony Brook, New York 11794, USA; email: krishna.veeramah@stonybrook.edu.

Funding

Dynamics of Contemporary Genomic Evolution in Replicate Threespine Stickleback PopulationsR01GM124330 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI VEERAMAH, KRISHNA R · 2017 to 2021
$1.6M
NIGMS NIH HHS R01 GM124330
6 · The paper itself

Abstract

The repeated adaptation of oceanic threespine sticklebacks to fresh water has made it a premier organism to study parallel evolution. These small fish have multiple distinct ecotypes that display a wide range of diverse phenotypic traits. Ecotypes are easily crossed in the laboratory, and families are large and develop quickly enough for quantitative trait locus analyses, positioning the threespine stickleback as a versatile model organism to address a wide range of biological questions. Extensive genomic resources, including linkage maps, a high-quality reference genome, and developmental genetics tools have led to insights into the genomic basis of adaptation and the identification of genomic changes controlling traits in vertebrates. Recently, threespine sticklebacks have been used as a model system to identify the genomic basis of highly complex traits, such as behavior and host-microbiome and host-parasite interactions. We review the latest findings and new avenues of research that have led the threespine stickleback to be considered a supermodel of evolutionary genomics.

Indexed as

SmegmamorphaAnimalsChromosome MappingGenomicsHumansPhenotypeQuantitative Trait LocibehaviorGasterosteus aculeatusgenetic architecturehost–microbiome interactionsparasitesrapid parallel adaptationstanding genetic variationvertebrate evolution

Identifiers

PMID33909459
PMCPMC8415275

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.