ReviewNeuroimmunomodulation2021
SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface.
Review in Neuroimmunomodulation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Virtual reality enhanced mindfulness and yoga intervention for postpartum depression and anxiety in the post COVID era.Scientific reports · 2025Trial
- The effect of COVID-19 on placental functioning in South African pregnancies: investigation of kisspeptin expression and vascular and inflammatory alterations.Histochemistry and cell biology · 2025Article
- In need of robust evidence of non-association of pregestational and early pregnancy SARS-CoV-2 infections with congenital anomalies.EClinicalMedicine · 2024Review
- Viral infections in pregnancy and impact on offspring neurodevelopment: mechanisms and lessons learned.Pediatric research · 2024Review
- Neonatal outcomes of maternal prenatal coronavirus infection.Pediatric research · 2024Review
- Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection.Brain : a journal of neurology · 2023Article
- Neuroimaging assessment of pediatric cerebral changes associated with SARS-CoV-2 infection during pregnancy.Frontiers in pediatrics · 2023Article
- Congenital heart disease in a patient with COVID-19 infection during early pregnancy: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022Article
- Decidual immune response following COVID-19 during pregnancy varies by timing of maternal SARS-CoV-2 infection.Journal of reproductive immunology · 2022Article
- COVID-19 in pregnancy: implications for fetal brain development.Trends in molecular medicine · 2022Review
- SARS-CoV-2 (COVID-19) as a possible risk factor for neurodevelopmental disorders.Frontiers in neuroscience · 2022Review
- Virus-Induced Maternal Immune Activation as an Environmental Factor in the Etiology of Autism and Schizophrenia.Frontiers in neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has devastating effects on the population worldwide. Given this scenario, the extent of the impact of the disease on more vulnerable individuals, such as pregnant women, is of great concern. Although pregnancy may be a risk factor in respiratory virus infections, there are no considerable differences regarding COVID-19 severity observed between pregnant and nonpregnant women. In these circumstances, an emergent concern is the possibility of neurodevelopmental and neuropsychiatric harm for the offspring of infected mothers. Currently, there is no stronger evidence indicating vertical transmission of SARS-CoV-2; however, the exacerbated inflammatory response observed in the disease could lead to several impairments in the offspring's brain. Furthermore, in the face of historical knowledge on possible long-term consequences for the progeny's brain after infection by viruses, we must consider that this might be another deleterious facet of COVID-19. In light of neuroimmune interactions at the maternal-fetal interface, we review here the possible harmful outcomes to the offspring brains of mothers infected by SARS-CoV-2.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.