ArticleKidney international reports2021
Performance and Determinants of Serum Creatinine and Cystatin C-Based GFR Estimating Equations in South Asians.
Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Construct a classification decision tree model to select the optimal equation for estimating glomerular filtration rate and estimate it more accurately.Scientific reports · 2022Trial
- Development and Analytical Validation of a Smartphone-Based Quantitative Lateral Flow Immunoassay for Serum Cystatin-C.Journal of clinical laboratory analysis · 2026Article
- Dual Burden of Kidney Disease and Cognitive Impairment in the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia-Cohort.Kidney international reports · 2026Article
- Clinical insights on "Finerenone in type 1 diabetes and chronic kidney disease: short-term efficacy and safety insights".International urology and nephrology · 2026Article
- A Systematic Review Evaluating Estimated GFR Performance in South Asian Populations.Kidney international reports · 2026Article
- Impact of Adopting the Race/Ethnicity-Free 2021 CKD-EPI Equation on Cardiovascular Risk Stratification in a Multiethnic European Population: Results from the HELIUS Study.Global heart · 2026Article
- Association of self-reported anxiety and depressive symptoms with incident hypertension among young adults.Frontiers in cardiovascular medicine · 2026Article
- Kidney function estimation equations: a narrative review.Irish journal of medical science · 2025Review
- Evaluation of Race-Neutral Glomerular Filtration Rate Estimating Equations in an Indian Population.Kidney international reports · 2024Article
- International prevalence patterns of low eGFR in adults aged 18-60 without traditional risk factors from population-based cross-sectional studies: a disadvantaged populations eGFR epidemiology (DEGREE) study.medRxiv : the preprint server for health sciences · 2024Article
- Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study.Health technology assessment (Winchester, England) · 2024Article
- Comparison of Glomerular Filtration Rate Equations in a Rural New Mexico Cohort: Results from the COMPASS Study.medRxiv : the preprint server for health sciences · 2024Article
- Article
- Discordance Between Creatinine-Based and Cystatin C-Based Estimated GFR: Interpretation According to Performance Compared to Measured GFR.Kidney medicine · 2023Article
- Article
- Whole and cortical kidney volume predict 5-year post-nephrectomy eGFR in Indian living kidney donors.Nephrology (Carlton, Vic.) · 2023Article
- Review
- European Kidney Function Consortium Equation vs. Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) Refit Equations for Estimating Glomerular Filtration Rate: Comparison with CKD-EPI Equations in the Korean Population.Journal of clinical medicine · 2022Article
- Performance of Serum β2-Microglobulin- and β-Trace Protein-Based Panel Markers and 2021 Creatinine- and Cystatin-Based GFR Estimating Equations in Pakistan.Kidney medicine · 2022Article
- Discrepancies in estimated glomerular filtration rate and albuminuria levels in ethnic minority groups - The multiethnic HELIUS cohort study.EClinicalMedicine · 2022Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
introductionThe creatinine-based Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimated glomerular filtration rate (eGFR) equation was calibrated for the general Pakistan population (eGFRcr-PK) to eliminate bias and improve accuracy. Cystatin C-based CKD-EPI equations (eGFRcys and eGFRcr-cys) have not been assessed in this population, and non-GFR determinants of cystatin C are unknown.
methodsWe assessed eGFRcys, eGFRcr-cys, and non-GFR determinants of cystatin C in a cross-sectional study of 557 participants (≥40 years of age) from Pakistan. We compared bias (median difference in measured GFR [mGFR] and eGFR), precision (interquartile range [IQR] of differences), accuracy (percentage of eGFR within 30% of mGFR), root mean square error (RMSE), and classification of mGFR <60 ml/min/1.73 m
resultsWe found that eGFRcys underestimated mGFR (bias, 12.7 ml/min/1.73 m
conclusioneGFRcys underestimated mGFR in South Asians and eGFRcr-cys did not offer substantial advantage compared with eGFRcr-PK. Future studies are warranted to better understand the large bias in eGFRcys and non-GFR determinants of cystatin C in South Asians.
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