Evidence map›Paper›PMID 33916037›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Novel Concept of Micro Patterned Micro Titer Plates Fabricated via UV-NIL for Automated Neuronal Cell Assay Read-Out.

Mirko Lohse, Manuel W Thesen, Anja Haase, Martin Smolka, Nerea Briz Iceta, Ana Ayerdi Izquierdo, Isbaal Ramos, Clarisa Salado, Arne Schleunitz

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mirko LohseMicro Resist Technology GmbH, Köpenicker Str. 325, 12555 Berlin, Germany.
Manuel W ThesenMicro Resist Technology GmbH, Köpenicker Str. 325, 12555 Berlin, Germany.
Anja HaaseJoanneum Research Materials, Institute for Surface Technologies and Photonics, 8160 Weiz, Austria.ORCID 0000-0001-6838-9823
Martin SmolkaJoanneum Research Materials, Institute for Surface Technologies and Photonics, 8160 Weiz, Austria.ORCID 0000-0002-4742-8288
Nerea Briz IcetaTECNALIA, Basque Research and Technology Alliance (BRTA), Mikeletegi Pasealekua 2, 20009 Donostia-San Sebastián, Spain.
Ana Ayerdi IzquierdoTECNALIA, Basque Research and Technology Alliance (BRTA), Mikeletegi Pasealekua 2, 20009 Donostia-San Sebastián, Spain.ORCID 0000-0002-5680-6340
Isbaal RamosInnoprot, Parque Tecnológico de Bizkaia, Edificio 502, Primera Planta, 48160 Derio-Bizkaia, Spain.
Clarisa SaladoInnoprot, Parque Tecnológico de Bizkaia, Edificio 502, Primera Planta, 48160 Derio-Bizkaia, Spain.
Arne SchleunitzMicro Resist Technology GmbH, Köpenicker Str. 325, 12555 Berlin, Germany.

Funding

Horizon 2020 646260Horizon 2020 862092
6 · The paper itself

Abstract

The UV-nanoimprint lithography(UV-NIL) fabrication of a novel network of micron-sized channels, forming an open channel microfluidic system is described. Details about the complete manufacturing process, from mastering to fabrication in small batches and in high throughput with up to 1200 micro titer plates per hour is presented. Deep insight into the evaluation of a suitable UV-curable material, mr-UVCur26SF is given, presenting cytotoxic evaluation, cell compatibility tests and finally a neuronal assay. The results indicate how the given pattern, in combination with the resist, paves the way to faster, cheaper, and more reliable drug screening.

Indexed as

nanoimprint lithographyneuronal cell assayR2R UV-NIL

Identifiers

PMID33916037
PMCPMC8065385

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.