Evidence map›Paper›PMID 33916281›Full record

ArticleJournal of clinical medicine2021

Statin Use Is Associated with a Decreased Risk of Mortality among Patients with COVID-19.

Chieh-Chen Wu, An-Jen Lee, Chun-Hsien Su, Chu-Ya Huang, Md Mohaimenul Islam, Yung-Ching Weng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Mortality in People with Type 2 Diabetes Following SARS-CoV-2 Infection: A Population Level Analysis of Potential Risk Factors.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2022
    Article
  8. Article
  9. Metabolic Reprogramming in COVID-19.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chieh-Chen WuDepartment of Healthcare Information and Management, School of Health Technology, Ming Chuan University, Taipei 333, Taiwan.ORCID 0000-0003-2205-5849
An-Jen LeeDepartment of Healthcare Information and Management, School of Health Technology, Ming Chuan University, Taipei 333, Taiwan.
Chun-Hsien SuGraduate Institute of Sport Coaching Science, College of Kinesiology and Health, Chinese Culture University, Taipei 11114, Taiwan.
Chu-Ya HuangDepartment of Healthcare Information and Management, School of Health Technology, Ming Chuan University, Taipei 333, Taiwan.
Md Mohaimenul IslamGraduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-6026-2748
Yung-Ching WengDepartment of Healthcare Information and Management, School of Health Technology, Ming Chuan University, Taipei 333, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent epidemiological studies remain controversial regarding the association between statin use and reducing the risk of mortality among individuals with COVID-19.

objectiveThe objective of this study was to clarify the association between statin use and the risk of mortality among patients with COVID-19.

methodsWe conducted a systematic articles search of online databases (PubMed, EMBASE, Scopus, and Web of Science) between 1 February 2020 and 20 February 2021, with no restriction on language. The following search terms were used: "Statins" and "COVID-19 mortality or COVID19 mortality or SARS-CoV-2 related mortality". Two authors individually examined all articles and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for study inclusion and exclusion. The overall risk ratio (RRs) with 95% confidence interval (CI) was calculated to show the strength of the association and the heterogeneity among the studies was presented Q and

resultsTwenty-eight studies were assessed for eligibility and 22 studies met the inclusion criteria. Statin use was associated with a significantly decreased risk of mortality among patients with COVID-19 (RR

conclusionThis comprehensive study showed that statin use is associated with a decreased risk of mortality among individuals with COVID-19. A randomized control trial is needed to confirm and refute the association between them.

Indexed as

COVID-19diabetesmortality riskSARS-CoV-2statin

Identifiers

PMID33916281
PMCPMC8036545

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.