Evidence map›Paper›PMID 33916567›Full record

ArticleMolecules (Basel, Switzerland)2021

Increase in Autoantibodies-Abzymes with Peroxidase and Oxidoreductase Activities in Experimental Autoimmune Encephalomyelitis Mice during the Development of EAE Pathology.

Anna S Tolmacheva, Kseniya S Aulova, Andrey E Urusov, Irina A Orlovskaya, Georgy A Nevinsky

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anna S TolmachevaInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Kseniya S AulovaInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Andrey E UrusovInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Irina A OrlovskayaInstitute of Clinical Immunology, Siberian Branch of the Russian Academy of Medical Sciences, 630090 Novosibirsk, Russia.
Georgy A NevinskyInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-4988-8923
Institute of Chemical Biology and Fundamental Medicine · RU

Funding

Russian Foundation for Basic Research 20-04-00281Russian Science Foundation 19-15-00145
6 · The paper itself

Abstract

The exact mechanisms of multiple sclerosis (MS) development are still unknown, but the development of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice is associated with the violation of bone marrow hematopoietic stem cells (HSCs) differentiation profiles associated with the production of harmful for human's autoantibodies hydrolyzing myelin basic protein, myelin oligodendrocyte glycoprotein (MOG

Indexed as

AnimalsAntibodies, CatalyticAutoantibodiesCell DifferentiationCell ProliferationEncephalomyelitis, Autoimmune, ExperimentalHematopoietic Stem CellsHumansHydrogen PeroxideImmunoglobulin GMiceMice, Inbred C57BLMyelin Basic ProteinMyelin-Oligodendrocyte GlycoproteinOxidation-ReductionOxidoreductasesAntibodies, CatalyticAutoantibodiesHydrogen PeroxideImmunoglobulin GMyelin Basic ProteinMyelin-Oligodendrocyte Glycoproteinmyelin oligodendrocyte glycoprotein (35-55)OxidoreductasesPeptide FragmentsPeroxidasesC57BL/6 micecatalytic antibodiesEAE modelperoxidase and oxidoreductase activities

Identifiers

PMID33916567
PMCPMC8038483
OpenAlexW3149818881

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.