Evidence map›Paper›PMID 33916640›Full record

ReviewJournal of personalized medicine2021

Nuclear Medicine Imaging in Neuroblastoma: Current Status and New Developments.

Atia Samim, Godelieve A M Tytgat, Gitta Bleeker, Sylvia T M Wenker, Kristell L S Chatalic, Alex J Poot, Nelleke Tolboom, Max M van Noesel, Marnix G E H Lam, Bart de Keizer

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. [European journal of nuclear medicine and molecular imaging · 2023
    Trial
  3. [JMIR research protocols · 2026
    Article
  4. Article
  5. Revista de neurologia · 2026
    Article
  6. Article
  7. Prognostic value of baseline [68Ga]Ga‑DOTA‑NOC PET/CT in paediatric neuroblastoma.European journal of nuclear medicine and molecular imaging · 2026
    Article
  8. Article
  9. [EJNMMI reports · 2025
    Article
  10. SUV normalisation and reference tissue selection for [European journal of nuclear medicine and molecular imaging · 2025
    Observational
  11. Review
  12. Review
  13. Recommendations for the use of nuclear medicine imaging in patients with neuroblastoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  14. Review
  15. A multiparameter diagnostic model based on 2-[Quantitative imaging in medicine and surgery · 2025
    Article
  16. The value ofQuantitative imaging in medicine and surgery · 2025
    Article
  17. [Frontiers in oncology · 2025
    Article
  18. Research process of PET tracers for neuroendocrine tumors diagnosis.American journal of nuclear medicine and molecular imaging · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Atia SamimPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Godelieve A M TytgatPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Gitta BleekerDepartment of Radiology and Nuclear Medicine, Northwest Clinics, Wilhelminalaan 12, 1815 JD Alkmaar, The Netherlands.
Sylvia T M WenkerPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Kristell L S ChatalicPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Alex J PootPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Nelleke TolboomPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Max M van NoeselPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.ORCID 0000-0003-0503-5838
Marnix G E H LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht/Wilhelmina Children's Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Bart de KeizerPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.ORCID 0000-0002-6270-9483
Heidelberg University · DEPrincess Máxima Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is the most common extracranial solid malignancy in children. At diagnosis, approximately 50% of patients present with metastatic disease. These patients are at high risk for refractory or recurrent disease, which conveys a very poor prognosis. During the past decades, nuclear medicine has been essential for the staging and response assessment of neuroblastoma. Currently, the standard nuclear imaging technique is

Indexed as

[11C]mHED[123I]mIBG[124I]mIBG[18F]FDG[18F]F-DOPA[18F]mFBG[68Ga]Ga-DOTA peptidesneuroblastomanuclear medicineradionuclide imaging

Identifiers

PMID33916640
PMCPMC8066332
OpenAlexW3140948861

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.