Evidence map›Paper›PMID 33916974›Full record

ReviewNutrients2021

Endocannabinoids and the Gut-Brain Control of Food Intake and Obesity.

Nicholas V DiPatrizio

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. The critical role of gut-brain signalling in eating behaviour and obesity.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  2. Review
  3. Obesity and Gut-Brain Communication: The Cholinergic-Endocannabinoid Link.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Endocannabinoid System and Metabolism: The Influences of Sex.International journal of molecular sciences · 2024
    Review
  8. Cholinergic Neurotransmission Controls Orexigenic Endocannabinoid Signaling in the Gut in Diet-Induced Obesity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Nicholas V DiPatrizioDivision of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA 92521, USA.ORCID 0000-0001-8423-0695
University of California, Riverside · US

Funding

Gut-brain endocannabinoid signaling in feeding behavior and obesityR01DK119498 · NIDDK · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI DIPATRIZIO, NICHOLAS VINCENT · 2019 to 2023
$1.7M
NIDDK NIH HHS L30 DK114978NIDDK NIH HHS R01 DK119498NIH HHS DK114978NIH HHS DK119498Tobacco-Related Disease Research Program (TRDRP) from the University of California Office of the President T29KT0232
6 · The paper itself

Abstract

Gut-brain signaling controls food intake and energy homeostasis, and its activity is thought to be dysregulated in obesity. We will explore new studies that suggest the endocannabinoid (eCB) system in the upper gastrointestinal tract plays an important role in controlling gut-brain neurotransmission carried by the vagus nerve and the intake of palatable food and other reinforcers. A focus will be on studies that reveal both indirect and direct interactions between eCB signaling and vagal afferent neurons. These investigations identify (

Indexed as

AnimalsBrainEatingEndocannabinoidsGastrointestinal TractHumansObesitySynaptic TransmissionEndocannabinoidsCB1 receptorendocannabinoidfood intakegut-brainintestinereward

Identifiers

PMID33916974
PMCPMC8067588
OpenAlexW3140715558

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.